ID Q5E4K5_ALIF1 Unreviewed; 433 AA. AC Q5E4K5; DT 15-MAR-2005, integrated into UniProtKB/TrEMBL. DT 15-MAR-2005, sequence version 1. DT 02-JUN-2021, entry version 72. DE RecName: Full=Anaerobic C4-dicarboxylate transporter {ECO:0000256|PIRNR:PIRNR004539}; GN OrderedLocusNames=VF_1546 {ECO:0000313|EMBL:AAW86041.1}; OS Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri). OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; OC Aliivibrio. OX NCBI_TaxID=312309 {ECO:0000313|EMBL:AAW86041.1, ECO:0000313|Proteomes:UP000000537}; RN [1] {ECO:0000313|EMBL:AAW86041.1, ECO:0000313|Proteomes:UP000000537} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 700601 / ES114 {ECO:0000313|Proteomes:UP000000537}; RX PubMed=15703294; DOI=10.1073/pnas.0409900102; RA Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., RA Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., RA Stevens A., Visick K., Whistler C., Greenberg E.P.; RT "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with RT pathogenic congeners."; RL Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005). CC -!- FUNCTION: Responsible for the transport of C4-dicarboxylates from the CC periplasm across the inner membrane. {ECO:0000256|ARBA:ARBA00003625, CC ECO:0000256|PIRNR:PIRNR004539}. CC -!- SUBCELLULAR LOCATION: Cell inner membrane CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|PIRNR:PIRNR004539}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429, CC ECO:0000256|PIRNR:PIRNR004539}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. CC {ECO:0000256|ARBA:ARBA00006413, ECO:0000256|PIRNR:PIRNR004539}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000020; AAW86041.1; -; Genomic_DNA. DR RefSeq; WP_011262120.1; NC_006840.2. DR RefSeq; YP_204929.1; NC_006840.2. DR STRING; 312309.VF_1546; -. DR EnsemblBacteria; AAW86041; AAW86041; VF_1546. DR KEGG; vfi:VF_1546; -. DR PATRIC; fig|312309.11.peg.1564; -. DR eggNOG; COG2704; Bacteria. DR HOGENOM; CLU_036056_1_1_6; -. DR OMA; RQGCELK; -. DR OrthoDB; 591678at2; -. DR Proteomes; UP000000537; Chromosome I. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:InterPro. DR InterPro; IPR004668; Anaer_Dcu_memb_transpt. DR PANTHER; PTHR36106; PTHR36106; 1. DR Pfam; PF03605; DcuA_DcuB; 1. DR PIRSF; PIRSF004539; C4-dicrbxl_trns; 1. DR TIGRFAMs; TIGR00770; Dcu; 1. PE 3: Inferred from homology; KW Cell inner membrane {ECO:0000256|PIRNR:PIRNR004539}; KW Cell membrane {ECO:0000256|PIRNR:PIRNR004539}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR004539}; KW Reference proteome {ECO:0000313|Proteomes:UP000000537}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR004539}. FT TRANSMEM 20..42 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 49..68 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 88..111 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 165..188 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 225..243 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 263..281 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 293..315 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 335..359 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 366..390 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 410..432 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 433 AA; 45674 MW; 69BA48428833C166 CRC64; MSVIIEISVV LICIYWGLKM GGLGVGLAGG FGLAVLTLGL GLEPSAPAID VILIIMSVVT AASTMQAAGG MEWLVHHAGN LMRRHPKYIN ILAPIITWCM TIMAGTGYTV FSTLPVISEV AKEIGERPSR PLSAAVVASQ VAISGSPISA AMAAMISIME PAGVSFLQIM AICLPASFIA AMVAAFIASR QGCELKDDVV YQQIQKENKQ HVTSMTKDID PKAKYSVFLF ALATCAIVLY AAIPSLRPAF PSGDIMTTRD IIIVSMFAAA CLMVPMCNIH PDRIIKTTTF RSGMSSVAVI LGIVTMGSTV VNAHLPEIKE FAGSLLHSYP MLLSLVLFGT CTLLMSQGAT TPLIVPLALS LNVPHWAILA SFVAVTGVFV LPTYPTSLAA IEFDSTGSTR MGKNIFDHPF MLPGLTGVIV AIGFGFLLAP AVL //