ID Q5CZI2_HUMAN Unreviewed; 1180 AA. AC Q5CZI2; DT 29-MAR-2005, integrated into UniProtKB/TrEMBL. DT 29-MAR-2005, sequence version 1. DT 22-NOV-2017, entry version 93. DE SubName: Full=Uncharacterized protein DKFZp686D12108 {ECO:0000313|EMBL:CAI56714.1}; DE Flags: Fragment; GN Name=DKFZp686D12108 {ECO:0000313|EMBL:CAI56714.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAI56714.1}; RN [1] {ECO:0000313|EMBL:CAI56714.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Fetal kidney {ECO:0000313|EMBL:CAI56714.1}; RG The German cDNA Consortium; RA Bloecker H., Boecher M., Brandt P., Mewes H.W., Weil B., Amid C., RA Osanger A., Fobo G., Han M., Wiemann S.; RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX648241; CAI56714.1; -; mRNA. DR UniGene; Hs.369840; -. DR ProteinModelPortal; Q5CZI2; -. DR MaxQB; Q5CZI2; -. DR PaxDb; Q5CZI2; -. DR PeptideAtlas; Q5CZI2; -. DR PRIDE; Q5CZI2; -. DR eggNOG; ENOG410IMYX; Eukaryota. DR eggNOG; ENOG4111DVZ; LUCA. DR HOGENOM; HOG000072712; -. DR HOVERGEN; HBG006498; -. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro. DR CDD; cd00255; nidG2; 1. DR Gene3D; 4.10.800.10; -; 2. DR InterPro; IPR026823; cEGF. DR InterPro; IPR001881; EGF-like_Ca-bd_dom. DR InterPro; IPR013032; EGF-like_CS. DR InterPro; IPR000742; EGF-like_dom. DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site. DR InterPro; IPR018097; EGF_Ca-bd_CS. DR InterPro; IPR024731; EGF_dom. DR InterPro; IPR006605; G2_nidogen/fibulin_G2F. DR InterPro; IPR009017; GFP. DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf. DR InterPro; IPR003886; NIDO_dom. DR InterPro; IPR000716; Thyroglobulin_1. DR InterPro; IPR036857; Thyroglobulin_1_sf. DR Pfam; PF12662; cEGF; 1. DR Pfam; PF12947; EGF_3; 1. DR Pfam; PF07645; EGF_CA; 2. DR Pfam; PF07474; G2F; 1. DR Pfam; PF06119; NIDO; 1. DR Pfam; PF00086; Thyroglobulin_1; 2. DR SMART; SM00181; EGF; 5. DR SMART; SM00179; EGF_CA; 4. DR SMART; SM00682; G2F; 1. DR SMART; SM00539; NIDO; 1. DR SMART; SM00211; TY; 2. DR SUPFAM; SSF54511; SSF54511; 1. DR SUPFAM; SSF57184; SSF57184; 2. DR SUPFAM; SSF57610; SSF57610; 2. DR PROSITE; PS00010; ASX_HYDROXYL; 2. DR PROSITE; PS01186; EGF_2; 3. DR PROSITE; PS50026; EGF_3; 4. DR PROSITE; PS01187; EGF_CA; 1. DR PROSITE; PS51220; NIDO; 1. DR PROSITE; PS50993; NIDOGEN_G2; 1. DR PROSITE; PS00484; THYROGLOBULIN_1_1; 2. DR PROSITE; PS51162; THYROGLOBULIN_1_2; 2. PE 2: Evidence at transcript level; KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00500, KW ECO:0000256|SAAS:SAAS00601599}; KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076, KW ECO:0000256|SAAS:SAAS00602928}; KW Repeat {ECO:0000256|SAAS:SAAS00594563}. FT DOMAIN 110 275 NIDO. {ECO:0000259|PROSITE:PS51220}. FT DOMAIN 530 760 Nidogen G2 beta-barrel. FT {ECO:0000259|PROSITE:PS50993}. FT DOMAIN 761 802 EGF-like. {ECO:0000259|PROSITE:PS50026}. FT DOMAIN 803 845 EGF-like. {ECO:0000259|PROSITE:PS50026}. FT DOMAIN 850 893 EGF-like. {ECO:0000259|PROSITE:PS50026}. FT DOMAIN 894 930 EGF-like. {ECO:0000259|PROSITE:PS50026}. FT DOMAIN 939 1007 Thyroglobulin type-1. FT {ECO:0000259|PROSITE:PS51162}. FT DOMAIN 1018 1086 Thyroglobulin type-1. FT {ECO:0000259|PROSITE:PS51162}. FT DISULFID 976 983 {ECO:0000256|PROSITE-ProRule:PRU00500}. FT DISULFID 1056 1063 {ECO:0000256|PROSITE-ProRule:PRU00500}. FT NON_TER 1 1 {ECO:0000313|EMBL:CAI56714.1}. SQ SEQUENCE 1180 AA; 129673 MW; 3DADEC2BFAAEDC29 CRC64; TPQTERITHS SVSWSFLLRF SRGKLLMLRA AALHPDELFP HGESWGDQLL QEGDDESSAV VKLANPLHFY EARFSNLYVG TNGIISTQDF PRETQYVDYD FPTDFPAIAP FLADIDTSHG RGRVLYREDT SPAVLGLAAR YVRAGFPRSA RFTPTHAFLA TWEQVGAYEE VKRGALPSGE LNTFQAVLAS DGSDSYALFL YPANGLQFLG TRPKESYNVQ LQLPARVGFC RGEADDLKSE GPYFSLTSTE QSVKNLYQLS NLGIPGVWAF HIGSTSPLDN VRPAAVGDLS AAHSSVPLGR SFSHATALES DYNEDNLDYY DVNEEEAEYL PGEPEEALNG HSSIDVSFQS KVDTKHLEES STLDPHTKEG TSLGEVGGPD LKGQVEPWDE RETRSPAPPE VDRDSLAPSW ETPPPYPENG SIQPYPDGGP VPSEMDVPPA HPEEEIVLRS YPASDHTTPL SRGTYEVGLE DNIGSNTEVF TYNAANKETC EHNHRQCSRH AFCTDYATGF CCHCQSKFYG NGKHCLPEGA PHRVNGKVSG HLHVGHTPVH FTDVDLHAYI VGNDGRAYTA ISHIPQPAAQ ALLPLTPIGG LFGWLFALEK PGSENGFSLA GAAFTHDMEV TFYPGEETVR ITQTAEGLDP ENYLSIKTNI QGQVPYVSAN FTAHISPYKE LYHYSDSTVT STSSRDYSLT FGAINQTWSY RIHQNITYQV CRHAPRHPSF PTTQQLNVDR VFALYNDEER VLRFAVTNQI GPVKEDSDPT PVNPCYDGSH MCDTTARCHP GTGVDYTCEC ASGYQGDGRN CVDENECATG FHRCGPNSVC INLPGSYRCE CRSGYEFADD RHTCILITPP ANPCEDGSHT CAPAGQARCV HHGGSTFSCA CLPGYAGDGH QCTDVDECSE NRCHPAATCY NTPGSFSCRC QPGYYGDGFQ CIPDSTSSLT PCEQQQRHAQ AQYAYPGARF HIPQCDEQGN FLPLQCHGST GFCWCVDPDG HEVPGTQTPP GSTPPHCGPS PEPTQRPPTI CERWRENLLE HYGGTPRDDQ YVPQCDDLGH FIPLQCHGKS DFCWCVDKDG REVQGTRSQP GTTPACIPTV APPMVRPTPR PDVTPPSVGT FLLYTQGQQI GYLPLNGTRL QKDAAKTLLS LHVKWISPVG GRAAWLSQWE PPHRPCCSEV DWCREVLEGF //