ID Q5APD4_CANAL PRELIMINARY; PRT; 513 AA. AC Q5APD4; DT 10-MAY-2005 (TrEMBLrel. 30, Created) DT 10-MAY-2005 (TrEMBLrel. 30, Last sequence update) DT 24-JAN-2006 (TrEMBLrel. 32, Last annotation update) DE Potential cyclopropane-fatty-acyl-phospholipid synthase. GN Name=CFA1; ORFNames=CaO19.12294, CaO19.4831; OS Candida albicans SC5314. OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. OX NCBI_TaxID=237561; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SC5314; RX PubMed=15123810; DOI=10.1073/pnas.0401648101; RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., RA Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., RA Davis R.W., Scherer S.; RT "The diploid genome sequence of Candida albicans."; RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC -!- FUNCTION: Catalyzes the methyl transfer from S-adenosyl-methionine CC to the C-24 of zymosterol to form fecosterol (By similarity). CC -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + 5-alpha-cholesta- CC 8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5- CC alpha-cholest-8-en-3-beta-ol. CC -!- PATHWAY: Ergosterol biosynthesis. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AACQ01000002; EAL04623.1; -; Genomic_DNA. DR EMBL; AACQ01000001; EAL04819.1; -; Genomic_DNA. DR GO; GO:0008825; F:cyclopropane-fatty-acyl-phospholipid syntha...; IEA. DR GO; GO:0016740; F:transferase activity; IEA. DR GO; GO:0016126; P:sterol biosynthesis; IEA. DR InterPro; IPR003333; CMAS. DR InterPro; IPR001601; Methyltransf. DR InterPro; IPR000051; SAM_bd. DR Pfam; PF02353; CMAS; 1. KW Methyltransferase; Steroid biosynthesis; Sterol biosynthesis; KW Transferase. SQ SEQUENCE 513 AA; 58777 MW; 3CA020873BCD76B4 CRC64; MLDDVAFIKT PAAKKQPPAS NECGVWTTDS PAIHNAPLPA DGPGSTSFSN TILFSILALV PGYITYKLGL GFKTWVFFFL ILAIPILMAY WSIMSTFSPR INEKVKYPNR PISYYLEFHT PELKAKYETS NGGKGSKIPI ETFQELYFDG KVSFKGDCLD VLEYKHDWAS FRFTLGLFRF FLLGMIPEVI FHSQSQDEEQ VRDHYDRGDD FYTWFLGPRM IYTSGVISDI TREETLEELQ DNKLTVMADK IDLKKGDHVL DIGCGWGTWT TFASSKYGAN VTGITLGRNQ TKWGNTLLKE YGIPSDQSRI VCCDYRDAPK SSKPSGKYDK ITSVEMAEHV GIRRLTAYLE QCRDALEDDG LLFLQYSGLR KNWQYEDLEW GLFMNKYIFP GADASTPLSF FASCMESVGF EIVSVDNIGV HYSATLWRWY RNWIGNKDKV VNKYGVKWYR IWEFFLGSSV VASRNGTATC YQFICRKNIN SYRRIDYVPQ QKGLQGPVQE GTKWAKEFTN FYD //