ID Q5APD4_CANAL PRELIMINARY; PRT; 513 AA. AC Q5APD4; DT 10-MAY-2005 (TrEMBLrel. 30, Created) DT 10-MAY-2005 (TrEMBLrel. 30, Last sequence update) DT 10-MAY-2005 (TrEMBLrel. 30, Last annotation update) DE Potential cyclopropane-fatty-acyl-phospholipid synthase. GN Name=CFA1; ORFNames=CaO19.12294, CaO19.4831; OS Candida albicans SC5314. OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. OX NCBI_TaxID=237561; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SC5314; RX PubMed=15123810; DOI=10.1073/pnas.0401648101; RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., RA Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., RA Davis R.W., Scherer S.; RT "The diploid genome sequence of Candida albicans."; RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SC5314; RA Dungan J., Kuo A., Newport G., Lan C.-Y., Iijima C., Adegbola O., RA Roberts J., Persson K., Donnelly S., Favoreto S., Tzung K.-W., RA Jones T., Scherer S., Agabian N.; RT "Annotation of the Genome of Candida albicans."; RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the methyl transfer from S-adenosyl-methionine CC to the C-24 of zymosterol to form fecosterol (By similarity). CC -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + 5-alpha-cholesta- CC 8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5- CC alpha-cholest-8-en-3-beta-ol. CC -!- PATHWAY: Ergosterol biosynthesis. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AACQ01000002; EAL04623.1; -; Genomic_DNA. DR EMBL; AACQ01000001; EAL04819.1; -; Genomic_DNA. KW Lipid synthesis; Methyltransferase; Steroid biosynthesis; KW Sterol biosynthesis; Transferase. SQ SEQUENCE 513 AA; 58776 MW; 3CA020873BCD76B4 CRC64; MLDDVAFIKT PAAKKQPPAS NECGVWTTDS PAIHNAPLPA DGPGSTSFSN TILFSILALV PGYITYKLGL GFKTWVFFFL ILAIPILMAY WSIMSTFSPR INEKVKYPNR PISYYLEFHT PELKAKYETS NGGKGSKIPI ETFQELYFDG KVSFKGDCLD VLEYKHDWAS FRFTLGLFRF FLLGMIPEVI FHSQSQDEEQ VRDHYDRGDD FYTWFLGPRM IYTSGVISDI TREETLEELQ DNKLTVMADK IDLKKGDHVL DIGCGWGTWT TFASSKYGAN VTGITLGRNQ TKWGNTLLKE YGIPSDQSRI VCCDYRDAPK SSKPSGKYDK ITSVEMAEHV GIRRLTAYLE QCRDALEDDG LLFLQYSGLR KNWQYEDLEW GLFMNKYIFP GADASTPLSF FASCMESVGF EIVSVDNIGV HYSATLWRWY RNWIGNKDKV VNKYGVKWYR IWEFFLGSSV VASRNGTATC YQFICRKNIN SYRRIDYVPQ QKGLQGPVQE GTKWAKEFTN FYD //