ID MON1_CANAL Reviewed; 565 AA. AC Q5A723; DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot. DT 26-APR-2005, sequence version 1. DT 11-NOV-2015, entry version 47. DE RecName: Full=Vacuolar fusion protein MON1; GN Name=MON1; ORFNames=CaO19.8109; OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; OC Candida/Lodderomyces clade; Candida. OX NCBI_TaxID=237561; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SC5314 / ATCC MYA-2876; RX PubMed=15123810; DOI=10.1073/pnas.0401648101; RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., RA Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., RA Davis R.W., Scherer S.; RT "The diploid genome sequence of Candida albicans."; RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004). CC -!- FUNCTION: Required for multiple vacuole delivery pathways CC including the cytoplasm to vacuole transport (Cvt), autophagy, CC pexophagy and endocytosis. {ECO:0000250}. CC -!- SUBCELLULAR LOCATION: Endosome, multivesicular body membrane CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. CC Prevacuolar compartment membrane {ECO:0000250}; Peripheral CC membrane protein {ECO:0000250}. Vacuole membrane {ECO:0000250}; CC Peripheral membrane protein {ECO:0000250}. CC -!- SIMILARITY: Belongs to the MON1/SAND family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AACQ01000054; EAK98465.1; -; Genomic_DNA. DR RefSeq; XP_717431.1; XM_712338.1. DR EnsemblFungi; EAK98465; EAK98465; CaO19.8109. DR GeneID; 3640881; -. DR KEGG; cal:CaO19.8109; -. DR CGD; CAL0073400; orf19.8109. DR InParanoid; Q5A723; -. DR OrthoDB; EOG78M09Q; -. DR Proteomes; UP000000559; Unassembled WGS sequence. DR GO; GO:0000329; C:fungal-type vacuole membrane; IBA:GO_Central. DR GO; GO:0035658; C:Mon1-Ccz1 complex; IBA:GO_Central. DR GO; GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW. DR GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central. DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central. DR InterPro; IPR004353; Vacuolar_fusion_protein_MON1. DR PANTHER; PTHR13027; PTHR13027; 2. DR Pfam; PF03164; Mon1; 1. DR PRINTS; PR01546; YEAST73DUF. PE 3: Inferred from homology; KW Autophagy; Complete proteome; Endosome; Membrane; Protein transport; KW Reference proteome; Transport; Vacuole. FT CHAIN 1 565 Vacuolar fusion protein MON1. FT /FTId=PRO_0000278856. SQ SEQUENCE 565 AA; 64521 MW; 0DB9DBEABB1513FE CRC64; MSFPKTLNVP DKSSLLVPQT TKASATGPTT AVSYETASSE IRSIRESPYL PSSPVDSQQF DGRSIISTSG MSEYIADLND LPSIRHDINP TSIKTGGTGS RSFKFSNCFQ TLDSELSNMD FFTKYISISK GDDKAQFNNK LKHFFIFSSA GKPIYSMNGS DDIVIGYMGI LTTIVSSFQE NFNQELQVLE LGQGLKIVAV NKSPIILISI SKLSFETVES VHLQLDTLYC YLIGILSKSV IDKHFNNRLN YDLRRILSPL DFENLDELCL NLTYGIPNTS DRTQDSTFGL YTSQVLLPLS RESVKIRHTL RSKLNSIVNT NNEDVLFTIL LSGNGKILNY LHPKQHNLPN KDLNMLLFII HSLLKNQSQQ DEDLWLPLCM PTFNDHGFLY VFVRQWQDLV LMLISGSKNS FDALKLSANE ICTKLNNKQE LAVKLINELS IPLSIEVPFV FKHFIYKDIR LNQFVMSELP THEFSSFQFL KCYNELKVSQ AKIIKHDNNL NYKKLTYLQD RDITGFMLMD KYYEFYCIIE RSSEQETITS KKLIQISSQI IRWCKKNHAR LFVTI //