ID Q59289 PRELIMINARY; PRT; 659 AA. AC Q59289; DT 01-NOV-1996 (TREMBLREL. 01, CREATED) DT 01-NOV-1996 (TREMBLREL. 01, LAST SEQUENCE UPDATE) DT 01-JAN-1998 (TREMBLREL. 05, LAST ANNOTATION UPDATE) DE HEPARINASE III PROTEIN PRECURSOR (EC 4.2.2.8) DE (HEPARITIN-SULFATE LYASE) (HEPARIN-SULFATE ELIMINASE). GN HEPC. OS CYTOPHAGA HEPARINA. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; OC NONPHOTOSYNTHETIC, NONFRUITING GLIDING; CYTOPHAGACEAE. RN [1] RP SEQUENCE FROM N.A. RA SU H., BLAIN F., BENNETT C.; RL SUBMITTED (AUG-1995) TO EMBL/GENBANK/DDBJ DATA BANKS. RN [2] RP SEQUENCE FROM N.A. RA TKALEC A.L.; RL SUBMITTED (MAY-1995) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- CATALYTIC ACTIVITY: ELIMINATION OF SULFATE; APPEARS TO ACT ON CC LINKAGES BETWEEN N-ACETYL-D- GLUCOSAMINE AND URONATE. PRODUCT IS CC AN UNSATURATED SUGAR. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U27586; G924925; -. KW SIGNAL; LYASE. FT SIGNAL 1 24 POTENTIAL. FT CHAIN 25 659 SQ SEQUENCE 659 AA; 75806 MW; EB60B6B4 CRC32; MTTKIFKRII VFAVIALSSG NILAQSSSIT RKDFDHINLE YSGLEKVNKA VAAGNYDDAA KALLAYYREK SKAREPDFSN AEKPADIRQP IDKVTREMAD KALVHQFQPH KGYGYFDYGK DINWQMWPVK DNEVRWQLHR VKWWQAMALV YHATGDEKYA REWVYQYSDW ARKNPLGLSQ DNDKFVWRPL EVSDRVQSLP PTFSLFVNSP AFTPAFLMEF LNSYHQQADY LSTHYAEQGN HRLFEAQRNL FAGVSFPEFK DSPRWRQTGI SVLNTEIKKQ VYADGMQFEL SPIYHVAAID IFLKAYGSAK RVNLEKEFPQ SYVQTVENMI MALISISLPD YNTPMFGDSW ITDKNFRMAQ FASWARVFPA NQAIKYFATD GKQGKAPNFL SKALSNAGFY TFRSGWDKNA TVMVLKASPP GEFHAQPDNG TFELFIKGRN FTPDAGVFVY SGDEAIMKLR NWYRQTRIHS TLTLDNQNMV ITKARQNKWE TGNNLDVLTY TNPSYPNLDH QRSVLFINKK YFLVIDRAIG EATGNLGVHW QLKEDSNPVF DKTKNRVYTT YRDGNNLMIQ SLNADRTSLN EEEGKVSYVY NKELKRPAFV FEKPKKNAGT QNFVSIVYPY DGQKAPEISI RENKGNDFEK GKLNLTLTIN GKQQLVLVP //