ID Q59289_PEDHE Unreviewed; 659 AA. AC Q59289; DT 01-NOV-1996, integrated into UniProtKB/TrEMBL. DT 01-NOV-1996, sequence version 1. DT 28-NOV-2006, entry version 26. DE Heparinase III protein precursor (EC 4.2.2.8). GN Name=HepC; OS Pedobacter heparinus (Flavobacterium heparinum). OC Bacteria; Bacteroidetes; Sphingobacteria; Sphingobacteriales; OC Sphingobacteriaceae; Pedobacter. OX NCBI_TaxID=984; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=96316388; PubMed=8702264; RA Su H., Blain F., Musil R.A., Zimmermann J.J., Gu K., Bennett D.C.; RT "Isolation and expression in Escherichia coli of hepB and hepC, genes RT coding for the glycosaminoglycan-degrading enzymes heparinase II and RT heparinase III, respectively, from Flavobacterium heparinum."; RL Appl. Environ. Microbiol. 62:2723-2734(1996). RN [2] RP NUCLEOTIDE SEQUENCE. RA Tkalec A.L.; RL Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=96374394; PubMed=8780685; DOI=10.1006/bbrc.1996.1246; RA Godavarti R., Davis M., Venkataraman G., Cooney C., Langer R., RA Sasisekharan R.; RT "Heparinase III from Flavobacterium heparinum: cloning and recombinant RT expression in Escherichia coli."; RL Biochem. Biophys. Res. Commun. 225:751-758(1996). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U27586; AAB18278.1; -; Genomic_DNA. DR PIR; JC4910; JC4910. DR GO; GO:0015021; F:heparin-sulfate lyase activity; IEA:EC. DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW. DR InterPro; IPR012480; Hepar_II_III. DR Pfam; PF07940; Hepar_II_III; 1. KW Lyase; Signal. FT SIGNAL 1 24 Potential. FT CHAIN 25 659 Potential. FT /FTId=PRO_5000144614. SQ SEQUENCE 659 AA; 75807 MW; B73EDF10A1256FE2 CRC64; MTTKIFKRII VFAVIALSSG NILAQSSSIT RKDFDHINLE YSGLEKVNKA VAAGNYDDAA KALLAYYREK SKAREPDFSN AEKPADIRQP IDKVTREMAD KALVHQFQPH KGYGYFDYGK DINWQMWPVK DNEVRWQLHR VKWWQAMALV YHATGDEKYA REWVYQYSDW ARKNPLGLSQ DNDKFVWRPL EVSDRVQSLP PTFSLFVNSP AFTPAFLMEF LNSYHQQADY LSTHYAEQGN HRLFEAQRNL FAGVSFPEFK DSPRWRQTGI SVLNTEIKKQ VYADGMQFEL SPIYHVAAID IFLKAYGSAK RVNLEKEFPQ SYVQTVENMI MALISISLPD YNTPMFGDSW ITDKNFRMAQ FASWARVFPA NQAIKYFATD GKQGKAPNFL SKALSNAGFY TFRSGWDKNA TVMVLKASPP GEFHAQPDNG TFELFIKGRN FTPDAGVFVY SGDEAIMKLR NWYRQTRIHS TLTLDNQNMV ITKARQNKWE TGNNLDVLTY TNPSYPNLDH QRSVLFINKK YFLVIDRAIG EATGNLGVHW QLKEDSNPVF DKTKNRVYTT YRDGNNLMIQ SLNADRTSLN EEEGKVSYVY NKELKRPAFV FEKPKKNAGT QNFVSIVYPY DGQKAPEISI RENKGNDFEK GKLNLTLTIN GKQQLVLVP //