ID RIB7_METJA STANDARD; PRT; 224 AA. AC Q58085; DT 01-NOV-1997 (Rel. 35, Created) DT 01-NOV-1997 (Rel. 35, Last sequence update) DT 05-JUL-2004 (Rel. 44, Last annotation update) DE Putative 5-amino-6-(5-phosphoribosylamino)uracil reductase DE (EC 1.1.1.193) (HTP reductase). GN OrderedLocusNames=MJ0671; OS Methanococcus jannaschii. OC Archaea; Euryarchaeota; Methanococci; Methanococcales; OC Methanocaldococcaceae; Methanocaldococcus. OX NCBI_TaxID=2190; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=JAL-1 / DSM 2661 / ATCC 43067; RX MEDLINE=96337999; PubMed=8688087; RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., RA Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., RA Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., RA Overbeek R., Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., RA Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., RA Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., RA Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., RA Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.; RT "Complete genome sequence of the methanogenic archaeon, Methanococcus RT jannaschii."; RL Science 273:1058-1073(1996). CC -!- CATALYTIC ACTIVITY: 5-amino-6-(5-phosphoribitylamino)uracil + CC NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH. CC -!- PATHWAY: Riboflavin biosynthesis; third step. CC -!- SIMILARITY: Belongs to the HTP reductase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U67514; AAB98665.1; -. DR PIR; G64383; G64383. DR TIGR; MJ0671; -. DR InterPro; IPR002734; RibD_C. DR InterPro; IPR006401; Rib_reduct_arch. DR Pfam; PF01872; RibD_C; 1. DR TIGRFAMs; TIGR00227; ribD_Cterm; 1. DR TIGRFAMs; TIGR01508; rib_reduct_arch; 1. KW Complete proteome; Hypothetical protein; NADP; Oxidoreductase; KW Riboflavin biosynthesis. SQ SEQUENCE 224 AA; 25037 MW; 4D8C15CE291E89D8 CRC64; MVMVMEKKPY IISNVGMTLD GKLATINNDS RISCEEDLIR VHKIRANVDG IMVGIGTVLK DDPRLTVHKI KSDRNPVRIV VDSKLRVPLN ARVLNKDAKT IIATTEDTNE EKEKKIKILE DMGVEVVKCG RGKVDLKKLM DILYDKGIKS ILLEGGGTLN WGMFKEGLVD EVSVYIAPKI FGGKEAPTYV DGEGFKTVDE CVKLELKNFY RLGEGIVLEF KVKK //