ID Q56FN4_HUMAN Unreviewed; 266 AA. AC Q56FN4; DT 10-MAY-2005, integrated into UniProtKB/TrEMBL. DT 10-MAY-2005, sequence version 1. DT 10-FEB-2009, entry version 39. DE SubName: Full=MHC class II antigen; GN Name=HLA-DRB1; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=17174751; DOI=10.1016/j.humimm.2006.09.002; RA Balas A., Vilches C., Rodriguez M.A., Fernandez B., Martinez M.P., RA de Pablo R., Garcia-Sanchez F., Vicario J.L.; RT "Group-specific amplification of cDNA from DRB1 genes. Complete coding RT sequences of partially defined alleles and identification of the new RT alleles DRB1*040602, DRB1*111102, DRB1*080103, and DRB1*0113."; RL Hum. Immunol. 67:1008-1016(2006). CC -!- SIMILARITY: Contains 1 Ig-like C1-type (immunoglobulin-like) CC domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY961078; AAX63466.1; -; mRNA. DR UniGene; Hs.534322; -. DR UniGene; Hs.701691; -. DR SMR; Q56FN4; 34-220. DR IPI; IPI00876970; -. DR Ensembl; ENSG00000206240; Homo sapiens. DR Ensembl; ENSG00000206306; Homo sapiens. DR HGNC; HGNC:4948; HLA-DRB1. DR HOVERGEN; Q56FN4; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro. DR GO; GO:0002504; P:antigen processing and presentation of pept...; IEA:UniProtKB-KW. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003006; Ig/MHC_CS. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR014745; MHC_II_a/b_N. DR InterPro; IPR000353; MHC_II_b_N. DR Gene3D; G3DSA:2.60.40.10; Ig-like_fold; 1. DR Gene3D; G3DSA:3.10.320.10; MHC_II_alpha_N; 1. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF00969; MHC_II_beta; 1. DR ProDom; PD000328; MHC_II_beta; 1. DR SMART; SM00407; IGc1; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; 1. PE 2: Evidence at transcript level; KW Immune response; MHC II; Membrane; Transmembrane. SQ SEQUENCE 266 AA; 29928 MW; 463A93827B138F57 CRC64; MVCLRLPGGS CMAVLTVTLM VLSSPLALAG DTRPRFLEYS TGECYFFNGT ERVRFLDRYF YNQEEYVRFD SDVGEYRAVT ELGRPSAEYW NSQKDILEDR RAAVDTYCRH NYGVGESFTV QRRVHPKVTV YPSKTQPLQH HNLLVCSVSG FYPGSIEVRW FRNGQEEKTG VVSTGLIHNG DWTFQTLVML ETVPRSGEVY TCQVEHPSVT SPLTVEWSAR SESAQSKMLS GVGGFVLGLL FLGAGLFIYF RNQKGHSGLQ PTGFLS //