ID Q56FN4_HUMAN Unreviewed; 266 AA. AC Q56FN4; DT 10-MAY-2005, integrated into UniProtKB/TrEMBL. DT 10-MAY-2005, sequence version 1. DT 23-JAN-2007, entry version 21. DE MHC class II antigen. GN Name=HLA-DRB1; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RA Balas A., Vilches C., Rodriguez M.A., Fernandez B., Martinez M.P., RA de Pablo R., Garcia-Sanchez F., Vicario J.L.; RT "Group-Specific Amplification of cDNA From DRB1 Genes. Complete Coding RT Sequences of Partially Defined Alleles and Identification of the New RT Alleles DRB1*040602, DRB1*111102, DRB1*080103, and DRB1*0113."; RL Hum. Immunol. 67:1008-1016(2006). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY961078; AAX63466.1; -; mRNA. DR SMR; Q56FN4; 34-220. DR Ensembl; ENSG00000196444; Homo sapiens. DR HGNC; HGNC:4948; HLA-DRB1. DR RZPD-ProtExp; I0328; -. DR RZPD-ProtExp; I0335; -. DR RZPD-ProtExp; IOH13934; -. DR RZPD-ProtExp; IOH14748; -. DR RZPD-ProtExp; IOH21889; -. DR RZPD-ProtExp; IOH27972; -. DR RZPD-ProtExp; IOH3310; -. DR RZPD-ProtExp; IOH4220; -. DR RZPD-ProtExp; IOH6782; -. DR RZPD-ProtExp; IOH7183; -. DR RZPD-ProtExp; T7421; -. DR RZPD-ProtExp; T7448; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW. DR GO; GO:0002504; P:antigen processing and presentation of pept...; IEA:UniProtKB-KW. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR003006; Ig_MHC. DR InterPro; IPR000353; MHC_II_beta_N. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF00969; MHC_II_beta; 1. DR ProDom; PD000328; MHC_II_beta; 1. DR SMART; SM00407; IGc1; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; UNKNOWN_1. KW Immune response; MHC II; Membrane; Transmembrane. SQ SEQUENCE 266 AA; 29928 MW; 463A93827B138F57 CRC64; MVCLRLPGGS CMAVLTVTLM VLSSPLALAG DTRPRFLEYS TGECYFFNGT ERVRFLDRYF YNQEEYVRFD SDVGEYRAVT ELGRPSAEYW NSQKDILEDR RAAVDTYCRH NYGVGESFTV QRRVHPKVTV YPSKTQPLQH HNLLVCSVSG FYPGSIEVRW FRNGQEEKTG VVSTGLIHNG DWTFQTLVML ETVPRSGEVY TCQVEHPSVT SPLTVEWSAR SESAQSKMLS GVGGFVLGLL FLGAGLFIYF RNQKGHSGLQ PTGFLS //