ID Q55WS9_CRYNE PRELIMINARY; PRT; 365 AA. AC Q55WS9; DT 24-MAY-2005, integrated into UniProtKB/TrEMBL. DT 24-MAY-2005, sequence version 1. DT 05-SEP-2006, entry version 12. DE Hypothetical protein. GN ORFNames=CNBC0610; OS Cryptococcus neoformans var. neoformans B-3501A. OC Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Heterobasidiomycetes; OC Tremellomycetidae; Tremellales; Tremellaceae; Filobasidiella. OX NCBI_TaxID=283643; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=B-3501A; RA Fung E., Hyman R.W., Rowley D., Bruno D., Miranda M., Fukushima M., RA Wickes B.L., Fu J., Davis R.W.; RT "Cryptococcus neoformans serotype D sequencing."; RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC -!- FUNCTION: Kinase involved in a signal transduction pathway that is CC activated by changes in the osmolarity of the extracellular CC environment. Plays an essential role in maintaining water CC homeostasis (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC -!- SIMILARITY: Belongs to the Ser/Thr protein kinase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAEY01000013; EAL21920.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA. DR GO; GO:0004707; F:MAP kinase activity; IEA. DR GO; GO:0000166; F:nucleotide binding; IEA. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA. DR GO; GO:0016740; F:transferase activity; IEA. DR GO; GO:0006468; P:protein amino acid phosphorylation; IEA. DR InterPro; IPR008351; JNK_MAPK. DR InterPro; IPR011009; Kinase_like. DR InterPro; IPR003527; MAP_kin. DR InterPro; IPR008352; p38_MAPK. DR InterPro; IPR000719; Prot_kinase. DR InterPro; IPR008271; Ser_thr_pkin_AS. DR InterPro; IPR002290; Ser_thr_pkinase. DR Pfam; PF00069; Pkinase; 1. DR PRINTS; PR01772; JNKMAPKINASE. DR PRINTS; PR01773; P38MAPKINASE. DR ProDom; PD000001; Prot_kinase; 1. DR SMART; SM00220; S_TKc; 1. DR PROSITE; PS01351; MAPK; UNKNOWN_1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. KW ATP-binding; Hypothetical protein; Kinase; Nucleotide-binding; KW Serine/threonine-protein kinase; Transferase. SQ SEQUENCE 365 AA; 41213 MW; F28E2E95B6DAD6B5 CRC64; MADFVKLSIF GTVFEVTTRY VDLQPVGMGA FGLVCSAKDQ LSGTSVAIKK IMKPFSTPVL SKRTYRELKL LKHLRHENII SLSDIFISPL EDIYFVTELL GTDLHRLLTS RPLEKQFIQY FLYQILRGLK YVHSAGVVHR DLKPSNILVN ENCDLKICDF GLARIQDPQM TGYVSTRYYR APEIMLTWQK YDVAVDIWST GCIFAEMLEG KPLFPGKDHV NQFSIITELL GTPPDDVIQT IASENTLRFV QSLPKREKVP FSTKFPNADP VSLDLLEKML VFDPRTRISA AEGLAHEYLA PYHDPTDEPV AAEVFDWSFN DADLPVDTWK VMMYSEILDF HNLGDISQNE AEGPVTGEVP AAPAS //