ID Q54H45_DICDI Unreviewed; 690 AA. AC Q54H45; DT 24-MAY-2005, integrated into UniProtKB/TrEMBL. DT 24-MAY-2005, sequence version 1. DT 06-FEB-2007, entry version 17. DE Protein kinase, TKL group. GN ORFNames=DDB_0229954; OS Dictyostelium discoideum AX4. OC Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium. OX NCBI_TaxID=352472; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=AX4; RX PubMed=15875012; DOI=10.1038/nature03481; RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., RA Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., RA Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., RA Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., RA Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., RA Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., RA Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., RA Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., RA Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., RA Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., RA Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., RA Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., RA Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., RA Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., RA Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., RA Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., RA Kuspa A.; RT "The genome of the social amoeba Dictyostelium discoideum."; RL Nature 435:43-57(2005). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=AX4; RG The Dictyostelium discoideum Sequencing Consortium; RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.-A., RA Sucgang R., Song J., Cox E.C., Tunggal B., Szafranski K., RA Konfortov B.A., Farbrother P., Bankier A.T., Lehmann R., Hamlin N., RA Xu Q., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., RA Sodergren E., Davis P., Nie X., Kerhornou A., Hemphill L., Bason N., RA Berriman M., Desany B., Churcher C., Cooper J., van Driessche N., RA Cronin A., Goodhead I., Muzny D., Hall N., Harper D., Lindsay R., RA Hauser H., James K., Quiles M., Buchrieser C., Wardroper A., RA Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K., RA Price C., Ma J., Quail M., Hernandez J., Rabbinowitsch E., Steffen D., RA Sanders M., Weinstock G., Sharp S., Just E., Shaulsky G., Simmonds M., RA Tivey A., White B., Walker D., Woodward J., Winckler T., RA Schleicher M., Rosenthal A., Rivero F., Chisholm R.L., Gibbs R., RA Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H., RA Noegel A.A., Barrell B., Kuspa A.; RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC -!- SIMILARITY: Belongs to the Ser/Thr protein kinase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAFI02000148; EAL62566.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. DR GO; GO:0004713; F:protein-tyrosine kinase activity; IEA:InterPro. DR GO; GO:0006468; P:protein amino acid phosphorylation; IEA:InterPro. DR InterPro; IPR011009; Kinase_like. DR InterPro; IPR000719; Prot_kinase. DR InterPro; IPR008271; Ser_thr_pkin_AS. DR InterPro; IPR001245; Tyr_pkinase. DR Pfam; PF07714; Pkinase_Tyr; 1. DR PRINTS; PR00109; TYRKINASE. DR ProDom; PD000001; Prot_kinase; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. KW ATP-binding; Kinase; Membrane; Nucleotide-binding; KW Serine/threonine-protein kinase; Transferase; Tyrosine-protein kinase. SQ SEQUENCE 690 AA; 76041 MW; 5A0A8373D8D4DFE5 CRC64; MKVQIVFFSI TVFIFVLFLL SVESNTKIKI VPSFLENSNE IEDLYINLDS DSKSSEHTTS SSSSSNSKNK GDSSSSSSNS GSSSNSIISG DSNSKDAPTT SSDSLSPATP IPTDGLLSAS TYVTFTGGKV LCENITFCPN GYMYSSDYAC NYDIVQNDPA THRGDWNDGI KMFEDPLPKN TTIDQVEGIS FTISGAVGCQ VTSSATTLEF YIQDLLVLTN TTSRYDICTC GSCYVTFGTE VYKYNMLGYN ITGENKFQIQ VSVNSMCATT IGITLYYKPP TITPTPTITP TPTITPTPTI TPTVTPTATP STTPSTTPTT TPSTPTPTPT KSPYSGALSP QVKKYIIIAS SITGGLLISI FSFVFIRKRL NSKRSGYTQI KDGKDIDTQQ IKIGVRIGKG NFGEVYLGTW RGSQVAVKKL PAHNINENIL KEFHREINLM KNLRHPNVIQ FLGSCLISPD ICICTEYMPR GSLYSILHNE KIKISWSLVK RMMIDAAKGI IYLHGSTPVI LHRDLKSHNL LVDENWKVKV ADFGLSTIEQ QGATMTACGT PCWTSPEVLR SQRYTEKADV YSFGIILWEC ATRQDPYFGI PPFQVIFAVG REGMRPPTPK YGPPKYIQLL KDCLNENPSQ RPTMEQCLEI LESIETKGFD DIPVNNNNNN NSNNNENNNE NNNNSDNNNN DINYSNRVIN //