ID Q53YC7_HUMAN Unreviewed; 347 AA. AC Q53YC7; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 24-NOV-2009, entry version 18. DE SubName: Full=Pre-B-cell leukemia homeobox 1; DE SubName: Full=Pre-B-cell leukemia transcription factor 1; DE SubName: Full=Pre-B-cell leukemia transcription factor 1, isoform CRA_c; GN Name=PBX1; ORFNames=RP11-477H21.1-002, hCG_23011; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RA Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., RA Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., RA Phelan M., Farmer A.; RT "Cloning of human full-length CDSs in BD Creator(TM) System Donor RT vector."; RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., RA Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Beasley H.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE. RA Kay M.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BT006705; AAP35351.1; -; mRNA. DR EMBL; AL359255; CAI14856.1; -; Genomic_DNA. DR EMBL; AL357568; CAI14856.1; JOINED; Genomic_DNA. DR EMBL; AL357568; CAI14910.1; -; Genomic_DNA. DR EMBL; AL359255; CAI14910.1; JOINED; Genomic_DNA. DR EMBL; CH471067; EAW90741.1; -; Genomic_DNA. DR IPI; IPI00215683; -. DR UniGene; Hs.654412; -. DR STRING; Q53YC7; -. DR PRIDE; Q53YC7; -. DR Ensembl; ENST00000367897; ENSP00000356872; ENSG00000185630; Homo sapiens. DR Ensembl; ENST00000401534; ENSP00000384856; ENSG00000185630; Homo sapiens. DR UCSC; uc001gcs.1; human. DR HGNC; HGNC:8632; PBX1. DR PhylomeDB; Q53YC7; -. DR ArrayExpress; Q53YC7; -. DR Bgee; Q53YC7; -. DR GO; GO:0005634; C:nucleus; IDA:HPA. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:transcription factor activity; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR InterPro; IPR001356; Homeobox. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR009057; Homeodomain-like. DR InterPro; IPR012287; Homeodomain-rel. DR InterPro; IPR005542; PBX. DR Gene3D; G3DSA:1.10.10.60; Homeodomain-rel; 1. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF03792; PBC; 1. DR SMART; SM00389; HOX; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 2: Evidence at transcript level; KW DNA-binding; Homeobox; Nucleus. SQ SEQUENCE 347 AA; 38427 MW; C4A2BDDD4A410C20 CRC64; MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP TDPQLMRLDN MLLAEGVAGP EKGGGSAAAA AAAAASGGAG SDNSVEHSDY RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM NLLREQSRTR PISPKEIERM VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF NKQATEILNE YFYSHLSNPY PSEEAKEELA KKCGITVSQV SNWFGNKRIR YKKNIGKFQE EANIYAAKTA VTATNVSAHG SQANSPSTPN SAGGYPSPCY QPDRRIQ //