ID   SPC24_ASPFU             Reviewed;         200 AA.
AC   Q4X0I7;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 2.
DT   05-APR-2011, entry version 39.
DE   RecName: Full=Probable kinetochore protein spc24;
GN   Name=spc24; ORFNames=AFUA_2G13330;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Neosartorya.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S.,
RA   Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W.,
RA   Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S.,
RA   Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R.,
RA   Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A.,
RA   Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J.,
RA   Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J.,
RA   Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S.,
RA   Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A.,
RA   Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M.,
RA   Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I.,
RA   Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M.,
RA   Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S.,
RA   Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J.,
RA   White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K.,
RA   Machida M., Hall N., Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Acts as a component of the essential kinetochore-
CC       associated NDC80 complex, which is required for chromosome
CC       segregation and spindle checkpoint activity (By similarity).
CC   -!- SUBUNIT: Component of the NDC80 complex, which consists of at
CC       least ndc80, nuf2 and spc24 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity). Chromosome,
CC       centromere, kinetochore (By similarity). Note=Associated with
CC       kinetochores (By similarity).
CC   -!- SIMILARITY: Belongs to the SPC24 family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAL93628.1; Type=Erroneous gene model prediction;
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DR   EMBL; AAHF01000001; EAL93628.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_755666.1; XM_750573.1.
DR   ProteinModelPortal; Q4X0I7; -.
DR   SMR; Q4X0I7; 139-199.
DR   STRING; Q4X0I7; -.
DR   EnsemblFungi; CADAFUAT00004247; CADAFUAP00004247; CADAFUAG00004247.
DR   GeneID; 3513168; -.
DR   GenomeReviews; CM000170_GR; spc24.
DR   KEGG; afm:AFUA_2G13330; -.
DR   eggNOG; fuNOG13347; -.
DR   GeneTree; EFGT00050000003958; -.
DR   OrthoDB; EOG4K0TZ2; -.
DR   GO; GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   InterPro; IPR013252; Ndc80_Spc24.
DR   Pfam; PF08286; Spc24; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Centromere; Chromosome; Coiled coil;
KW   Complete proteome; Kinetochore; Mitosis; Nucleus.
FT   CHAIN         1    200       Probable kinetochore protein spc24.
FT                                /FTId=PRO_0000246658.
FT   COILED       39    129       Potential.
SQ   SEQUENCE   200 AA;  22783 MW;  1A83BFE1FFA0958D CRC64;
     MLLDEDPATL IHHTIGNFNI QPDKQAVTRI NDSLSTLQQS RELRMRDAES ALRKLSRNLH
     ALTAQHEEAV SSHDSAKHAA QMVELDTKKF RIAKAATELE IESERLEGEL EMLKERLAEL
     EAQGLEGDEA TRREREADDA TILRLKIYRS LGIDIEADEA GNFSKAVIRN SRKGDVHVVN
     MDPKFSRFFY ANYFWSTMQG
//