ID   Q4UCH0_THEAN            Unreviewed;      1146 AA.
AC   Q4UCH0;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   10-FEB-2021, entry version 44.
DE   RecName: Full=6-Cys domain-containing protein {ECO:0000259|PROSITE:PS51701};
GN   ORFNames=TA03640 {ECO:0000313|EMBL:CAI75481.1};
OS   Theileria annulata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI75481.1, ECO:0000313|Proteomes:UP000001950};
RN   [1] {ECO:0000313|EMBL:CAI75481.1, ECO:0000313|Proteomes:UP000001950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX   PubMed=15994557; DOI=10.1126/science.1110418;
RA   Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA   Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA   Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA   Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA   McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA   Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA   Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA   Shiels B., Tait A., Barrell B.G., Hall N.;
RT   "Genome of the host-cell transforming parasite Theileria annulata compared
RT   with T. parva.";
RL   Science 309:131-133(2005).
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000256|ARBA:ARBA00004241}.
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DR   EMBL; CR940352; CAI75481.1; -; Genomic_DNA.
DR   RefSeq; XP_954957.1; XM_949864.1.
DR   GeneID; 3864860; -.
DR   KEGG; tan:TA03640; -.
DR   VEuPathDB; PiroplasmaDB:TA03640; -.
DR   eggNOG; ENOG502TN29; Eukaryota.
DR   InParanoid; Q4UCH0; -.
DR   OMA; AGCETVN; -.
DR   OrthoDB; 964815at2759; -.
DR   Proteomes; UP000001950; Chromosome 3.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.2860; -; 1.
DR   InterPro; IPR010884; 6_CYS_dom.
DR   InterPro; IPR038160; 6_CYS_dom_sf.
DR   Pfam; PF07422; s48_45; 1.
DR   PROSITE; PS51701; 6_CYS; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001950};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..1146
FT                   /note="6-Cys domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004244370"
FT   DOMAIN          1020..1146
FT                   /note="6-Cys"
FT                   /evidence="ECO:0000259|PROSITE:PS51701"
FT   REGION          438..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          958..999
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        972..987
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1146 AA;  131941 MW;  2792B7B65345A299 CRC64;
     MKFILKLLLL AVFVEFADGL QELTCDFSSG EGSLSNKYIS ICVRKFGLLN KIDIICPKNP
     KGIVQPVNVK EDVEECEDDE AFFEYMDIIQ KLKNMDLNEK MKENNEEGEY TIIPEGVEEM
     YVLLKDELSN STKLDSYGVW DIFGTKTENV VSRTANAEKE IVTLKPPSDG IVTVKTYKIL
     MYICINKKHL SKINNNFLKL LRKILYRPSS EEYQNLYLPL LGGIDEDVRA GIAFIIPKDM
     PKVVNGCGNV PNRFFKNYQD YNRSRGFTEC KIDLMVSPFI GFYCEGIVKP IECLYSFKTI
     ETFSLITLEH HMIHNWGILE GRLNHVNYKT EQIYSSFRGY CDCLDRRGRI TARIIVERKT
     EHTFNLPQMI MKNRVRPIRG DWFEVTIHPG DKLKIILPPN RDNIECMNYI INRDIPKTIF
     GESETSENKD GEPIVVAEED ESEKECDISS EESESHMEED EYEEISSVEE EEEEWAIGFE
     DDEGSESDNP YCDMLFANSE IIKTLSSPSY QKTHTRKYPF FTLLSPIDIK THVNAYNCTS
     EIVTQMPISE LFGGNSLVID TSEVDKGILK IERKNKPLAM KKGIDDIYYY WILKYGWSKK
     PEIVAKINVI LAQTHDYCAG CETVNTGIFY NIKDAEFCKY HFNLCQKQGI KHNTFDITSH
     LQYGISCSED ERLYPPGYGS IVVDQRLNMV VNANEEIKTL EYPSIKNFKI FGKKTWQIIN
     IMTFYVSCLD PLGIEKSRLT LYYASYESHT NQGCFNYGEY ILLIPKVSMF LPPFDHTKYA
     RRGNNTNSLP ETECIPIPKN TLMYHLELRQ GTKFKLSVIK PKPLYLCEEV EIDHLRTPVI
     SNPNLTIKGV RKGHSFIPSD VYTDASYSSN RIFPVNLTKY TYRIFAGTDL DYLVPTEYSS
     MIATNVAGLK LKVLNYNNEF RYPFFENLVL YLPIGSIIII KSDILTSVDL IYASGSISEP
     EKPKSERSKD SLGGESTQQA TTSTGYDKNE NEGKEPPSID MRKMEIWGIH SIRVRGTNPW
     VHGCGVNGPS EDFFKDTEKI IENGSETGCR VDIREKEYAG FYCPEPYRVD PPGCFKYAYT
     GEYSRAVMMK DEILDDLWQE TNGFRYLKLK RNLRSQVLMT FLKRRPYVCF CRTVKGIMMS
     KIEVII
//