ID   COQ4_USTMA              Reviewed;         369 AA.
AC   Q4P5W8; A0A0D1DY01;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-JAN-2019, entry version 67.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111};
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 {ECO:0000255|HAMAP-Rule:MF_03111};
DE   Flags: Precursor;
GN   Name=COQ4 {ECO:0000255|HAMAP-Rule:MF_03111}; ORFNames=UMAG_04495;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T.,
RA   Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O.,
RA   Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J.,
RA   Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.,
RA   Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W.,
RA   Guzman P., Farman M.L., Stajich J.E., Sentandreu R.,
RA   Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA   Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M.,
RA   Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA   Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U.,
RA   Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W.,
RA   Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K.,
RA   Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen
RT   Ustilago maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G.,
RA   Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May
CC       play a role in organizing a multi-subunit COQ enzyme complex
CC       required for coenzyme Q biosynthesis. Required for steady-state
CC       levels of other COQ polypeptides. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex, composed
CC       of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_03111}; Peripheral membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
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DR   EMBL; CM003152; KIS67395.1; -; Genomic_DNA.
DR   RefSeq; XP_011390829.1; XM_011392527.1.
DR   STRING; 5270.UM04495P0; -.
DR   PRIDE; Q4P5W8; -.
DR   EnsemblFungi; KIS67395; KIS67395; UMAG_04495.
DR   GeneID; 23564661; -.
DR   KEGG; uma:UMAG_04495; -.
DR   EuPathDB; FungiDB:UMAG_04495; -.
DR   InParanoid; Q4P5W8; -.
DR   KO; K18586; -.
DR   OMA; PLHSIHI; -.
DR   OrthoDB; 1264469at2759; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000000561; Chromosome 13.
DR   Proteomes; UP000000561; Unassembled WGS sequence.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03111; Coq4; 1.
DR   InterPro; IPR007715; Coq4.
DR   InterPro; IPR027540; Coq4_euk.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 2.
PE   3: Inferred from homology;
KW   Complete proteome; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Transit peptide;
KW   Ubiquinone biosynthesis.
FT   TRANSIT       1     28       Mitochondrion. {ECO:0000255|HAMAP-
FT                                Rule:MF_03111}.
FT   CHAIN        29    369       Ubiquinone biosynthesis protein COQ4,
FT                                mitochondrial.
FT                                /FTId=PRO_0000388141.
SQ   SEQUENCE   369 AA;  40853 MW;  27471FD9BBD1F921 CRC64;
     MTSILGSARP LIQVGPKSRN ASTSMSRLPS FPTTRPCRRA PCSSSSYATI SPTAPRSSQR
     NPTNASRHPR IDEVDHIPTS ALGRVLLTAG SALGLLNNPS RGDLLSMLTQ VSSGPSLAHL
     LESMRSTESG RRLLIERPSV NSETVDVDYL ASLERGKFGR EWIEWLKDNG VGPDGRAEAD
     YMTTLEHKYL IQRYRESHDF YHLLLRMPVT QLGETVVKYF ELAQMNMPVA GFAAAGGTLR
     ILASSLSALP KPSQLISAAL NRSPAPETAH QPPSSADLSA LQTLIPWAMQ VGSSSVPLIS
     IEWERCWERD IEEMRREFRI TSPPIQVAKF SGRAKKGGKR RGWPSKILEH QKAQHQQQQQ
     QQKVDESRN
//