ID Q4JFB8_MOUSE Unreviewed; 106 AA. AC Q4JFB8; DT 02-AUG-2005, integrated into UniProtKB/TrEMBL. DT 02-AUG-2005, sequence version 1. DT 06-MAR-2013, entry version 34. DE SubName: Full=Protein-tyrosine-phosphatase; DE EC=3.1.3.48; DE Flags: Fragment; GN Name=Ptprf; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Balb/C; TISSUE=Whole brain; RX MEDLINE=93086603; PubMed=1454056; DOI=10.1007/BF00419663; RA Schepens J., Zeeuwen P., Wieringa B., Hendriks W.; RT "Identification and typing of members of the protein-tyrosine RT phosphatase gene family expressed in mouse brain."; RL Mol. Biol. Rep. 16:241-248(1992). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Balb/C; TISSUE=Whole brain; RA Hendriks W.W.; RL Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Balb/C; TISSUE=Whole brain; RX MEDLINE=95134232; PubMed=7832766; RA Hendriks W., Schepens J., Brugman C., Zeeuwen P., Wieringa B.; RT "A novel receptor-type protein tyrosine phosphatase with a single RT catalytic domain is specifically expressed in mouse brain."; RL Biochem. J. 305:499-504(1995). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z23049; CAA80584.1; -; mRNA. DR IPI; IPI00647973; -. DR UniGene; Mm.29855; -. DR ProteinModelPortal; Q4JFB8; -. DR STRING; Q4JFB8; -. DR MGI; MGI:102695; Ptprf. DR InParanoid; Q4JFB8; -. DR Bgee; Q4JFB8; -. DR Genevestigator; Q4JFB8; -. DR GO; GO:0005768; C:endosome; IEA:Compara. DR GO; GO:0060076; C:excitatory synapse; IEA:Compara. DR GO; GO:0030426; C:growth cone; IEA:Compara. DR GO; GO:0043025; C:neuronal cell body; IEA:Compara. DR GO; GO:0005886; C:plasma membrane; IEA:Compara. DR GO; GO:0042301; F:phosphate ion binding; IEA:Compara. DR GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IEA:Compara. DR GO; GO:0007156; P:homophilic cell adhesion; IEA:Compara. DR GO; GO:0031345; P:negative regulation of cell projection organization; IEA:Compara. DR GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Compara. DR GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IEA:Compara. DR GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IEA:Compara. DR GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Compara. DR GO; GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IEA:Compara. DR GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Compara. DR GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Compara. DR GO; GO:0050803; P:regulation of synapse structure and activity; IEA:Compara. DR InterPro; IPR000242; Tyr_Pase_rcpt/non-rcpt. DR Pfam; PF00102; Y_phosphatase; 1. DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1. PE 2: Evidence at transcript level; KW Hydrolase. FT NON_TER 1 1 FT NON_TER 106 106 SQ SEQUENCE 106 AA; 12192 MW; 1FFFE91130F040B2 CRC64; QRTATVVMMT RLEEKSRVKC DQYWPVRGTE TYGLIQVTLV DTVELATYTM RTFALHKSGS SEKRELRQFQ FMAWPDHGVP EYPTPILAFL RRVKACNPLD AGPMVV //