ID Q4G470_9CALI Unreviewed; 251 AA. AC Q4G470; DT 30-AUG-2005, integrated into UniProtKB/TrEMBL. DT 10-JUN-2008, sequence version 2. DT 03-MAR-2009, entry version 18. DE SubName: Full=RNA-dependent RNA polymerase; DE Flags: Fragment; OS Human calicivirus NLV/Hajmasker/487/2001/HUN. OC Viruses; ssRNA positive-strand viruses, no DNA stage; Caliciviridae; OC Norovirus. OX NCBI_TaxID=289513; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=NLV/Hajmasker/487/2001/HUN; RX PubMed=15977235; DOI=10.1002/jmv.20403; RA Reuter G., Krisztalovics K., Vennema H., Koopmans M., Szucs G.; RT "Evidence of the etiological predominance of norovirus in RT gastroenteritis outbreaks--emerging new-variant and recombinant RT noroviruses in Hungary."; RL J. Med. Virol. 76:598-607(2005). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=NLV/Hajmasker/487/2001/HUN; RX PubMed=16242995; DOI=10.1016/j.jcv.2005.07.012; RA Reuter G., Vennema H., Koopmans M., Szucs G.; RT "Epidemic spread of recombinant noroviruses with four capsid types in RT Hungary."; RL J. Clin. Virol. 35:84-88(2006). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=NLV/Hajmasker/487/2001/HUN; RA Reuter G., Vennema H., Koopmans M., Szucs G.; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). CC -!- SIMILARITY: Contains 1 RdRp catalytic domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY672563; AAT99643.2; -; Genomic_RNA. DR SMR; Q4G470; 1-48. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004386; F:helicase activity; IEA:InterPro. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro. DR GO; GO:0006350; P:transcription; IEA:InterPro. DR GO; GO:0019079; P:viral genome replication; IEA:InterPro. DR InterPro; IPR004004; Helicase/Pol/Pept_Calicivir. DR InterPro; IPR001205; RNA_pol_P3D. DR InterPro; IPR007094; RNA_pol_PSvir. DR Pfam; PF00680; RdRP_1; 1. DR PRINTS; PR00918; CALICVIRUSNS. DR PROSITE; PS50507; RDRP_SSRNA_POS; 1. PE 4: Predicted; KW Hydrolase; Nucleotide-binding; Nucleotidyltransferase; Protease; KW RNA replication; RNA-directed RNA polymerase; Thiol protease; KW Transferase. FT NON_TER 1 1 SQ SEQUENCE 251 AA; 28252 MW; 83045803E8310BD8 CRC64; EIMVKFSSEP HLAQVVAEDL LSPSVMDVGD FKISINEGLP SGVPCTSQWN SIAHWLLTLC ALSEVTDLSP DIIQANSLFS FYGDDEIVST DIKLDPEKLT TKLKEYGLKP TRPDKTEGPL IISEDLDGLT FLRRTVTRDP AGWFGKLDQS SILRQMYWTR GPNHEDPSET MIPHSQRPIQ LMSLLGEAAL HGPSFYSKIS KLVISELKEG GMDFYVPRQE PMFRWMRFSD LSTWEGDRNL APSFVNEDGV E //