ID Q497H5_MOUSE Unreviewed; 1309 AA. AC Q497H5; DT 13-SEP-2005, integrated into UniProtKB/TrEMBL. DT 13-SEP-2005, sequence version 1. DT 20-APR-2010, entry version 44. DE SubName: Full=Fat1 protein; DE Flags: Fragment; GN Name=Fat1; Synonyms=Fath; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6; TISSUE=Brain; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC100554; AAI00555.1; -; mRNA. DR IPI; IPI00874921; -. DR UniGene; Mm.27365; -. DR SMR; Q497H5; 1-142, 54-246, 539-701, 725-873. DR STRING; Q497H5; -. DR Ensembl; ENSMUST00000093529; ENSMUSP00000092968; ENSMUSG00000070047; Mus musculus. DR UCSC; uc009lom.1; mouse. DR MGI; MGI:109168; Fat1. DR eggNOG; roNOG11369; -. DR ArrayExpress; Q497H5; -. DR Bgee; Q497H5; -. DR Genevestigator; Q497H5; -. DR GO; GO:0030054; C:cell junction; IDA:MGI. DR GO; GO:0030175; C:filopodium; IDA:MGI. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0030027; C:lamellipodium; IDA:MGI. DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-KW. DR GO; GO:0005515; F:protein binding; IPI:MGI. DR GO; GO:0007015; P:actin filament organization; IMP:MGI. DR GO; GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI. DR GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro. DR InterPro; IPR002126; Cadherin. DR InterPro; IPR015919; Cadherin-like. DR InterPro; IPR020894; Cadherin_CS. DR InterPro; IPR008985; ConA-like_lec_gl. DR InterPro; IPR013320; ConA-like_subgrp. DR InterPro; IPR006209; EGF. DR InterPro; IPR006210; EGF-like. DR InterPro; IPR013032; EGF-like_reg_CS. DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site. DR InterPro; IPR000742; EGF_3. DR InterPro; IPR001881; EGF_Ca_bd. DR InterPro; IPR013091; EGF_Ca_bd_2. DR InterPro; IPR018097; EGF_Ca_bd_CS. DR InterPro; IPR001791; Laminin_G. DR InterPro; IPR012680; Laminin_G_2. DR Gene3D; G3DSA:2.60.40.60; Cadherin; 4. DR Gene3D; G3DSA:2.60.120.200; ConA_like_subgrp; 1. DR Pfam; PF00028; Cadherin; 2. DR Pfam; PF00008; EGF; 2. DR Pfam; PF07645; EGF_CA; 1. DR Pfam; PF02210; Laminin_G_2; 1. DR PRINTS; PR00205; CADHERIN. DR SMART; SM00112; CA; 4. DR SMART; SM00181; EGF; 3. DR SMART; SM00179; EGF_CA; 1. DR SMART; SM00282; LamG; 1. DR SUPFAM; SSF49313; Cadherin; 4. DR SUPFAM; SSF49899; ConA_like_lec_gl; 1. DR PROSITE; PS00010; ASX_HYDROXYL; 1. DR PROSITE; PS00232; CADHERIN_1; 2. DR PROSITE; PS50268; CADHERIN_2; 4. DR PROSITE; PS00022; EGF_1; 4. DR PROSITE; PS01186; EGF_2; 1. DR PROSITE; PS50026; EGF_3; 5. DR PROSITE; PS01187; EGF_CA; 1. DR PROSITE; PS50025; LAM_G_DOMAIN; 1. PE 2: Evidence at transcript level; KW Calcium; Cell adhesion; EGF-like domain; Membrane; Repeat; KW Transmembrane. FT NON_TER 1 1 SQ SEQUENCE 1309 AA; 143805 MW; 9A208181C4136D09 CRC64; ESLDYKSSHE YYLTVEATDG GTPSLSDVAT VNINVTDIND NSPVFSQDTY TTVVSEDAAL EQPVITIMAD DADGPSNSHI HYSIIEGNQG SPFTIDPVRG EVKVTKPLDR ETISGYTLTV QAADNGNPPR VNTTTVNIDV SDVNDNAPLF SRDNYSVIIQ ENKPVGFSVL KLVVTDKDSS HNGPPFFFTI VSGNDENAFE VNQHGVLLTA ATIKRKVKDH YLLHVKVADS GKPQLSSMTH IDIRVIEESI HPPAILPLEI FITAFGEEYS GGVIGKIHAT DQDVYDTLMY SLDPHMDGLF SVSSTGGKLI AHRKLDIGQY LLNVSVTDGK FTTVADITVH IQQVTQEMLN HTVAIRFANL TPEEFVGDYW RNFQRALRNI LGVRKNDIQI VSLQPSEPHS HLDVLLFVER SGGTHVSTKQ LLHKINSSVT DVEEIIGVRI LEVFQKLCAG LDCPWKFCDE KVSVDENVMS THSTARLSFV TPRHHRTAVC LCKDGTCPPV HHGCEDNPCP AGSECVADPR EEKYSCVCPG GGFGKCPGSS SITFTGNSFV KYRLLENENR LEMKLSMRLR TYSSHAVVMY ARGTDYSILE IHTGRLQYKF DCGSGPGIVS VQSIQVNDGQ WHAVSLEVEG NYAKLVLDEV HTASGTAPGA LKTLNLDNYV FFGGHLRQQG TKHGRGAQVA SGFRGCMDSI YLNGQELPLN NKPRAYAHIE EWVDLSHGCL LTATEDCSSS PCQNGGVCNP SPTGGYYCKC SALYVGTFCE VSVNPCSSNP CLYGGTCMVD NGGFVCQCRG LYTGQRCQLS PYCKDDPCKN GGTCFDSLDG AVCQCDSGFR GERCQSDIDE CAGNPCRNGA LCENTHGSYH CNCSQEYRGK HCEDASPNHY VSTPWNIGLA EGIGIIVFIA GIVLLVMVFV LCRKMISRKK KRQAEPEDKR LGPTTAFLQR PYFDSKLNKN IYSDIPPQVP VRPISYTPSI PSDSRNNLDR NSFEGSAIPE HPEFSTFNPE SMHGHRKAVA VCSVAPNLPP PPPSNSPSDS DSIQKPSWDF DYDAKVVDLD PCLSKKPLEE KPSQPYSARE SLSEVQSLSS FQSESCDDNE SLAAPDLSKP RGYHWDTSDW MPSVPLPDIQ EFPNYEAIDE HTPLYSADPN AIDTDYYPGG YDIESDFPPP PEDFPAPDEL PPLPPEFSDQ FESIHPPRDM PAAGSLGSSS RSRQRFNLNQ YLPNFYPADM SEPQKQGAGE NSPCREPYTP YPPGYQNFEA PTIENMPMSV YASTASCSDV SACCEVESEV MMSDYESGDD GHFEEVTIPP LDSQQHTEV //