ID Q3ZB92_DANRE Unreviewed; 351 AA. AC Q3ZB92; DT 27-SEP-2005, integrated into UniProtKB/TrEMBL. DT 27-SEP-2005, sequence version 1. DT 16-MAY-2012, entry version 67. DE SubName: Full=Novel protein similar to human protein kinase, cAMP-dependent, catalytic, beta (PRKACB, zgc:110804); DE SubName: Full=Protein kinase, cAMP-dependent, catalytic, beta; DE SubName: Full=Uncharacterized protein; GN Name=prkacbb; Synonyms=CH211-188C16.6, prkacb; GN ORFNames=CH211-188C16.6-001; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Singapore local strain; TISSUE=Embryo; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RA Holt K.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen; RG The Danio rerio Sequencing Project at the Sanger Institute; RT "The genomic sequence of Danio rerio."; RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases. RN [4] RP IDENTIFICATION. RC STRAIN=Tuebingen; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [5] RP IDENTIFICATION. RC STRAIN=Tuebingen; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC -!- SIMILARITY: Contains 1 AGC-kinase C-terminal domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CABZ01050553; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; FP015789; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC103487; AAI03488.1; -; mRNA. DR EMBL; CR848026; CAP09440.1; -; Genomic_DNA. DR IPI; IPI00493207; -. DR RefSeq; NP_001030148.1; NM_001034976.1. DR RefSeq; XP_003197858.1; XM_003197810.1. DR UniGene; Dr.21332; -. DR SMR; Q3ZB92; 14-351. DR STRING; Q3ZB92; -. DR Ensembl; ENSDART00000082143; ENSDARP00000076580; ENSDARG00000059125. DR Ensembl; ENSDART00000123112; ENSDARP00000105368; ENSDARG00000087866. DR GeneID; 100538234; -. DR GeneID; 563147; -. DR KEGG; dre:100538234; -. DR KEGG; dre:563147; -. DR CTD; 5567; -. DR CTD; 563147; -. DR ZFIN; ZDB-GENE-050904-4; prkacbb. DR eggNOG; COG0515; -. DR GeneTree; ENSGT00550000074358; -. DR HOGENOM; HOG000233033; -. DR HOVERGEN; HBG108317; -. DR InParanoid; Q3ZB92; -. DR KO; K04345; -. DR OMA; ENDILHF; -. DR OrthoDB; EOG4RXZ0C; -. DR NextBio; 20884756; -. DR Bgee; Q3ZB92; -. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. DR InterPro; IPR000961; AGC-kinase_C. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR000719; Prot_kinase_cat_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR002290; Ser/Thr_dual-sp_kinase_dom. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00133; S_TK_X; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; Kinase_like; 1. DR PROSITE; PS51285; AGC_KINASE_CTER; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 2: Evidence at transcript level; KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding; KW Reference proteome; Serine/threonine-protein kinase; Transferase. SQ SEQUENCE 351 AA; 40650 MW; 969567145CA2C677 CRC64; MGNAATAKKG NELESVKEFL AKAKEDFLRK WESPQQSTTC LDDFDRQKTL GTGSFGRVLL VKHKASDQYY AMKVLDKQKV VKLKQVEHTL NEKRILQAVS FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDQHGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLRNGVN DIKNHKWFAT TDWIAIYERK VEAPFIPKCR GPGDTSNFDD YEEEDIRVSV TEKCAKEFSE F //