ID Q3ZB92_DANRE Unreviewed; 351 AA. AC Q3ZB92; DT 27-SEP-2005, integrated into UniProtKB/TrEMBL. DT 27-SEP-2005, sequence version 1. DT 25-NOV-2008, entry version 30. DE SubName: Full=Zgc:110804 (Novel protein similar to human protein kinase, cAMP-dependent, catalytic, beta) (PRKACB, zgc:110804); GN Name=CH211-188C16.6; ORFNames=CH211-188C16.6-001, zgc:110804; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Singapore local strain; TISSUE=Embryo; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. RN [2] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY. RX PubMed=18307296; DOI=10.1021/pr700667w; RA Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., RA den Hertog J., Slijper M., Heck A.J.R.; RT "Online automated in vivo zebrafish phosphoproteomics: from large- RT scale analysis down to a single embryo."; RL J. Proteome Res. 7:1555-1564(2008). RN [3] RP NUCLEOTIDE SEQUENCE. RA Holt K.; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC103487; AAI03488.1; -; mRNA. DR EMBL; CR848026; CAP09440.1; -; Genomic_DNA. DR RefSeq; NP_001030148.1; -. DR UniGene; Dr.21332; -. DR SMR; Q3ZB92; 10-351. DR Ensembl; ENSDARG00000059125; Danio rerio. DR GeneID; 563147; -. DR KEGG; dre:563147; -. DR ZFIN; ZDB-GENE-050904-4; zgc:110804. DR HOGENOM; Q3ZB92; -. DR HOVERGEN; Q3ZB92; -. DR ArrayExpress; Q3ZB92; -. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. DR GO; GO:0006468; P:protein amino acid phosphorylation; IEA:InterPro. DR InterPro; IPR000961; AGC-kinase_C. DR InterPro; IPR017892; Pkinase_C. DR InterPro; IPR000719; Prot_kinase_core. DR InterPro; IPR017441; Protein_kinase_ATP_bd_CS. DR InterPro; IPR017442; Se/Thr_pkinase-rel. DR InterPro; IPR008271; Ser_thr_pkin_AS. DR InterPro; IPR002290; Ser_thr_pkinase. DR Pfam; PF00069; Pkinase; 1. DR Pfam; PF00433; Pkinase_C; 1. DR ProDom; PD000001; Prot_kinase; 1. DR SMART; SM00133; S_TK_X; 1. DR SMART; SM00220; S_TKc; 1. DR PROSITE; PS51285; AGC_KINASE_CTER; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 1: Evidence at protein level; KW ATP-binding; Kinase; Nucleotide-binding; KW Serine/threonine-protein kinase; Transferase. SQ SEQUENCE 351 AA; 40650 MW; 969567145CA2C677 CRC64; MGNAATAKKG NELESVKEFL AKAKEDFLRK WESPQQSTTC LDDFDRQKTL GTGSFGRVLL VKHKASDQYY AMKVLDKQKV VKLKQVEHTL NEKRILQAVS FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDQHGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLRNGVN DIKNHKWFAT TDWIAIYERK VEAPFIPKCR GPGDTSNFDD YEEEDIRVSV TEKCAKEFSE F //