ID Q3UX06_MOUSE Unreviewed; 190 AA. AC Q3UX06; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 16-APR-2014, entry version 52. DE SubName: Full=Putative uncharacterized protein; DE Flags: Fragment; GN Name=Parp1; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Methods Enzymol. 303:19-44(1999). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RX PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to RT prepare full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RX PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system--384-format RT sequencing pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RG The RIKEN Genome Exploration Research Group Phase II Team and the RG FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group RG Phase I and II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [6] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., RA Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., RA Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., RA Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., RA Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., RA Muramatsu M., Hayashizaki Y.; RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. RN [7] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RG The FANTOM Consortium; RG Riken Genome Exploration Research Group and Genome Science Group RG (Genome Network Project Core Group); RT "The Transcriptional Landscape of the Mammalian Genome."; RL Science 309:1559-1563(2005). RN [8] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=In vitro fertilized eggs; RX PubMed=16141073; DOI=10.1126/science.1112009; RG RIKEN Genome Exploration Research Group and Genome Science Group RG (Genome Network Project Core Group) and the FANTOM Consortium; RT "Antisense Transcription in the Mammalian Transcriptome."; RL Science 309:1564-1566(2005). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK135977; BAE22758.1; -; mRNA. DR UniGene; Mm.277779; -. DR PRIDE; Q3UX06; -. DR MGI; MGI:1340806; Parp1. DR HOVERGEN; HBG088594; -. DR InParanoid; Q3UX06; -. DR ArrayExpress; Q3UX06; -. DR Bgee; Q3UX06; -. DR Genevestigator; Q3UX06; -. DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl. DR GO; GO:0005730; C:nucleolus; IDA:MGI. DR GO; GO:0005654; C:nucleoplasm; IDA:MGI. DR GO; GO:0005634; C:nucleus; TAS:MGI. DR GO; GO:0043234; C:protein complex; IDA:MGI. DR GO; GO:0005667; C:transcription factor complex; IEA:Ensembl. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0051287; F:NAD binding; IEA:Ensembl. DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:Ensembl. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006284; P:base-excision repair; IMP:MGI. DR GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl. DR GO; GO:0042769; P:DNA damage response, detection of DNA damage; IEA:Ensembl. DR GO; GO:0006259; P:DNA metabolic process; IMP:MGI. DR GO; GO:0006281; P:DNA repair; TAS:MGI. DR GO; GO:0006302; P:double-strand break repair; IGI:MGI. DR GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IEA:Ensembl. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IEA:Ensembl. DR GO; GO:0016540; P:protein autoprocessing; IEA:Ensembl. DR GO; GO:0070212; P:protein poly-ADP-ribosylation; IEA:Ensembl. DR GO; GO:0040009; P:regulation of growth rate; IMP:MGI. DR GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl. DR GO; GO:0000723; P:telomere maintenance; IMP:MGI. DR GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl. DR Gene3D; 3.30.1740.10; -; 2. DR InterPro; IPR001510; Znf_PARP. DR Pfam; PF00645; zf-PARP; 2. DR PROSITE; PS00347; PARP_ZN_FINGER_1; 2. DR PROSITE; PS50064; PARP_ZN_FINGER_2; 2. PE 2: Evidence at transcript level; FT NON_TER 190 190 SQ SEQUENCE 190 AA; 21473 MW; FC5CB732F65A33F0 CRC64; MAEASERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRQPDVE VDGFSELRWD DQQKVKKTAE AGGVAGKGQD GSGGKAEKTL GDFLAEYAKS NRSMCKGCLE KIEKGQMRLS KKMVDPEKPQ LGMIDRWYHP TCFVKKRDEL GFRPEYSASQ LKGFSLLSAE //