ID Q3UTZ0_MOUSE Unreviewed; 386 AA. AC Q3UTZ0; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 23-MAR-2010, entry version 41. DE SubName: Full=Putative uncharacterized protein; DE Flags: Fragment; GN Name=Fzd6; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Aorta and vein; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). CC -!- SIMILARITY: Contains 1 FZ (frizzled) domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK138964; BAE23839.1; -; mRNA. DR IPI; IPI00117095; -. DR RefSeq; NP_001155966.1; -. DR RefSeq; NP_032082.3; -. DR UniGene; Mm.4769; -. DR STRING; Q3UTZ0; -. DR Ensembl; ENSMUST00000022906; ENSMUSP00000022906; ENSMUSG00000022297; Mus musculus. DR GeneID; 14368; -. DR KEGG; mmu:14368; -. DR CTD; 14368; -. DR MGI; MGI:108474; Fzd6. DR eggNOG; roNOG12804; -. DR HOVERGEN; HBG006977; -. DR InParanoid; Q3UTZ0; -. DR ArrayExpress; Q3UTZ0; -. DR Bgee; Q3UTZ0; -. DR Genevestigator; Q3UTZ0; -. DR GO; GO:0045177; C:apical part of cell; IDA:MGI. DR GO; GO:0016327; C:apicolateral plasma membrane; IDA:MGI. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. DR GO; GO:0004926; F:non-G-protein coupled 7TM receptor activity; IEA:InterPro. DR GO; GO:0001736; P:establishment of planar polarity; IGI:MGI. DR GO; GO:0007186; P:G-protein coupled receptor protein signalin...; IEA:UniProtKB-KW. DR GO; GO:0042472; P:inner ear morphogenesis; IGI:MGI. DR GO; GO:0001843; P:neural tube closure; IGI:MGI. DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW. DR GO; GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. DR InterPro; IPR000539; Frizzled. DR InterPro; IPR015526; Frizzled_related. DR InterPro; IPR017981; GPCR_2-like. DR PANTHER; PTHR11309; Fz_related; 1. DR Pfam; PF01534; Frizzled; 1. DR PRINTS; PR00489; FRIZZLED. DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1. PE 2: Evidence at transcript level; KW Developmental protein; G-protein coupled receptor; Membrane; Receptor; KW Transducer; Transmembrane; Wnt signaling pathway. FT NON_TER 1 1 SQ SEQUENCE 386 AA; 42124 MW; 038413B4EDC0B2FB CRC64; AVWFHAVAWG APGFLTVMLL AMNKVEGDNI SGVCFVGLYD LDASRYFVLL PLCLCVFVGL SLLLAGIISL NHVRQVIQHD GRNQEKLKKF MIRIGVFSGL YLVPLVTLLG CYVYELVNRI TWEMTWFSDH CHQYRIPCPY QANPKARPEL ALFMIKYLMT LIVGISAVFW VGSKKTCTEW AGFFKRNRKR DPISESRRVL QESCEFFLKH NSKVKHKKKH GAPGPHRLKV ISKSMGTSTG ATTNHGTSAM AIADHDYLGQ ETSTEVHTSP EASVKEGRAD RANTPSAKDR DCGESAGPSS KLSGNRNGRE SRAGGLKERS NGSEGAPSEG RVSPKSSVPE TGLIDCSTSQ AASSPEPTSL KGSTSLPVHS ASRARKEQGA GSHSDA //