ID Q3U8J6_MOUSE Unreviewed; 191 AA. AC Q3U8J6; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 17-FEB-2016, entry version 60. DE SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAE31022.1}; DE Flags: Fragment; GN Name=Ctsc {ECO:0000313|MGI:MGI:109553}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:BAE31022.1}; RN [1] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Methods Enzymol. 303:19-44(1999). RN [2] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to RT prepare full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [3] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system--384-format RT sequencing pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [4] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=11217851; DOI=10.1038/35055500; RG The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [5] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=12466851; DOI=10.1038/nature01266; RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [6] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., RA Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., RA Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., RA Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., RA Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., RA Muramatsu M., Hayashizaki Y.; RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. RN [7] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RG The FANTOM Consortium; RG Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group); RT "The Transcriptional Landscape of the Mammalian Genome."; RL Science 309:1559-1563(2005). RN [8] {ECO:0000313|EMBL:BAE31022.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAE31022.1}; RC TISSUE=Bone marrow {ECO:0000313|EMBL:BAE31022.1}; RX PubMed=16141073; DOI=10.1126/science.1112009; RG RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium; RT "Antisense Transcription in the Mammalian Transcriptome."; RL Science 309:1564-1566(2005). CC -!- SIMILARITY: Belongs to the peptidase C1 family. CC {ECO:0000256|RuleBase:RU362133}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK152192; BAE31022.1; -; mRNA. DR UniGene; Mm.322945; -. DR UniGene; Mm.483300; -. DR UniGene; Mm.89295; -. DR STRING; 10090.ENSMUSP00000032779; -. DR PaxDb; Q3U8J6; -. DR MGI; MGI:109553; Ctsc. DR eggNOG; COG4870; LUCA. DR eggNOG; KOG1543; Eukaryota. DR HOVERGEN; HBG011513; -. DR ChiTaRS; Ctsc; mouse. DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro. DR InterPro; IPR025661; Pept_asp_AS. DR InterPro; IPR025660; Pept_his_AS. DR InterPro; IPR013128; Peptidase_C1A. DR InterPro; IPR000668; Peptidase_C1A_C. DR PANTHER; PTHR12411; PTHR12411; 1. DR Pfam; PF00112; Peptidase_C1; 1. DR SMART; SM00645; Pept_C1; 1. DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1. DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1. PE 2: Evidence at transcript level; FT DOMAIN 1 186 Pept_C1. {ECO:0000259|SMART:SM00645}. FT NON_TER 1 1 {ECO:0000313|EMBL:BAE31022.1}. SQ SEQUENCE 191 AA; 21284 MW; DD23973C2C7982A1 CRC64; ILTNNSQTPI LSPQEVVSCS PYAQGCDGGF PYLIAGKYAQ DFGVVEESCF PYTAKDSPCK PRENCLRYYS SDYYYVGGFY GGCNEALMEL ELVKHGPMAV AFEVHDDFLH YHSGIYHHTG LSDPFNPFEL TNHAVLLVGY GRDPVTGIEY WIIKNSWGSN WGESGYFRIR RGTDECAIES IAVAAIPIPK L //