ID Q3U5B1_MOUSE Unreviewed; 333 AA.
AC Q3U5B1;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 29-MAY-2013, entry version 46.
DE SubName: Full=Putative uncharacterized protein;
GN Name=Mavs;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9;
RA Carninci P., Hayashizaki Y.;
RT "High-efficiency full-length cDNA cloning.";
RL Methods Enzymol. 303:19-44(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=11042159; DOI=10.1101/gr.145100;
RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M.,
RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.;
RT "Normalization and subtraction of cap-trapper-selected cDNAs to
RT prepare full-length cDNA libraries for rapid discovery of new genes.";
RL Genome Res. 10:1617-1630(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=11076861; DOI=10.1101/gr.152600;
RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P.,
RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M.,
RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A.,
RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K.,
RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M.,
RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J.,
RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.;
RT "RIKEN integrated sequence analysis (RISA) system--384-format
RT sequencing pipeline with 384 multicapillary sequencer.";
RL Genome Res. 10:1757-1771(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RG The RIKEN Genome Exploration Research Group Phase II Team and the
RG FANTOM Consortium;
RT "Functional annotation of a full-length mouse cDNA collection.";
RL Nature 409:685-690(2001).
RN [5]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group
RG Phase I and II Team;
RT "Analysis of the mouse transcriptome based on functional annotation of
RT 60,770 full-length cDNAs.";
RL Nature 420:563-573(2002).
RN [6]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,
RA Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,
RA Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,
RA Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,
RA Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,
RA Muramatsu M., Hayashizaki Y.;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RG The FANTOM Consortium, Riken Genome Exploration Research Group and
RG Genome Science Group (Genome Network Project Core Group);
RT "The Transcriptional Landscape of the Mammalian Genome.";
RL Science 309:1559-1563(2005).
RN [8]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=16141073; DOI=10.1126/science.1112009;
RG RIKEN Genome Exploration Research Group and Genome Science Group
RG (Genome Network Project Core Group) and the FANTOM Consortium;
RT "Antisense Transcription in the Mammalian Transcriptome.";
RL Science 309:1564-1566(2005).
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DR EMBL; AK153748; BAE32168.1; -; mRNA.
DR IPI; IPI01016267; -.
DR RefSeq; NP_001193311.1; NM_001206382.1.
DR RefSeq; NP_001193312.1; NM_001206383.1.
DR RefSeq; NP_001193314.1; NM_001206385.1.
DR UniGene; Mm.287226; -.
DR GeneID; 228607; -.
DR KEGG; mmu:228607; -.
DR CTD; 57506; -.
DR MGI; MGI:2444773; Mavs.
DR HOVERGEN; HBG079638; -.
DR InParanoid; Q3U5B1; -.
DR KO; K12648; -.
DR ChiTaRS; MAVS; mouse.
DR NextBio; 379056; -.
DR ArrayExpress; Q3U5B1; -.
DR Bgee; Q3U5B1; -.
DR Genevestigator; Q3U5B1; -.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:Compara.
DR GO; GO:0005739; C:mitochondrion; IDA:MGI.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:Compara.
DR GO; GO:0005777; C:peroxisome; IDA:MGI.
DR GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:Compara.
DR GO; GO:0042742; P:defense response to bacterium; IEA:Compara.
DR GO; GO:0045087; P:innate immune response; IEA:Compara.
DR GO; GO:0045071; P:negative regulation of viral genome replication; IEA:Compara.
DR GO; GO:0071651; P:positive regulation of chemokine (C-C motif) ligand 5 production; IEA:Compara.
DR GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:MGI.
DR GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
DR GO; GO:0032727; P:positive regulation of interferon-alpha production; IEA:Compara.
DR GO; GO:0032728; P:positive regulation of interferon-beta production; IEA:Compara.
DR GO; GO:0032757; P:positive regulation of interleukin-8 production; IEA:Compara.
DR GO; GO:0071660; P:positive regulation of IP-10 production; IEA:Compara.
DR GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Compara.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Compara.
DR GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara.
DR GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IEA:Compara.
DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
DR GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Compara.
DR GO; GO:0032481; P:positive regulation of type I interferon production; IMP:MGI.
DR GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Compara.
DR GO; GO:1900063; P:regulation of peroxisome organization; IEA:Compara.
DR GO; GO:0039529; P:RIG-I signaling pathway; IGI:MGI.
DR InterPro; IPR026148; Mt_antiviral_sig_pro.
DR PANTHER; PTHR21446; PTHR21446; 1.
PE 2: Evidence at transcript level;
SQ SEQUENCE 333 AA; 34389 MW; 8AEC8828800F1773 CRC64;
MSGGSLIPSP NQQALSPQPS REHQEQEPEL GGAHAANVAS VPIATYGPVS PTVSFQPLPR
TALRTNLLSG VTVSALSADT SLSSSSTGSA FAKGAGDQAK AATCFSTTLT NSVTTSSVPS
PRLVPVKTMS SKLPLSSKST AAMTSTVLTN TAPSKLPSNS VYAGTVPSRV PASVAKAPAN
TIPPERNSKQ AKETPEGPAT KVTTGGNQTG PNSSIRSLHS GPEMSKPGVL VSQLDEPFSA
CSVDLAISPS SSLVSEPNHG PEENEYSSFR IQVDESPSAD LLGSPEPLAT QQPQEEEEHC
ASSMPWAKWL GATSALLAVF LAVMLYRSRR LAQ
//