ID Q3U5B1_MOUSE Unreviewed; 333 AA. AC Q3U5B1; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 03-OCT-2012, entry version 41. DE SubName: Full=Putative uncharacterized protein; GN Name=Mavs; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX MEDLINE=99279253; PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Methods Enzymol. 303:19-44(1999). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX MEDLINE=20499374; PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to RT prepare full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX MEDLINE=20530913; PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system--384-format RT sequencing pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The RIKEN Genome Exploration Research Group Phase II Team and the RG FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group RG Phase I and II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [6] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., RA Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., RA Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., RA Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., RA Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., RA Muramatsu M., Hayashizaki Y.; RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. RN [7] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The FANTOM Consortium, Riken Genome Exploration Research Group and RG Genome Science Group (Genome Network Project Core Group); RT "The Transcriptional Landscape of the Mammalian Genome."; RL Science 309:1559-1563(2005). RN [8] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX PubMed=16141073; DOI=10.1126/science.1112009; RG RIKEN Genome Exploration Research Group and Genome Science Group RG (Genome Network Project Core Group) and the FANTOM Consortium; RT "Antisense Transcription in the Mammalian Transcriptome."; RL Science 309:1564-1566(2005). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK153748; BAE32168.1; -; mRNA. DR IPI; IPI01016267; -. DR RefSeq; NP_001193311.1; NM_001206382.1. DR RefSeq; NP_001193312.1; NM_001206383.1. DR RefSeq; NP_001193314.1; NM_001206385.1. DR UniGene; Mm.287226; -. DR UniGene; Mm.488165; -. DR STRING; Q3U5B1; -. DR GeneID; 228607; -. DR KEGG; mmu:228607; -. DR UCSC; uc008mld.1; mouse. DR CTD; 57506; -. DR MGI; MGI:2444773; Mavs. DR HOVERGEN; HBG079638; -. DR InParanoid; Q3U5B1; -. DR KO; K12648; -. DR NextBio; 379056; -. DR ArrayExpress; Q3U5B1; -. DR Bgee; Q3U5B1; -. DR Genevestigator; Q3U5B1; -. DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:Compara. DR GO; GO:0005739; C:mitochondrion; IDA:MGI. DR GO; GO:0005778; C:peroxisomal membrane; IEA:Compara. DR GO; GO:0004871; F:signal transducer activity; IEA:Compara. DR GO; GO:0002218; P:activation of innate immune response; IEA:Compara. DR GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:Compara. DR GO; GO:0042742; P:defense response to bacterium; IEA:Compara. DR GO; GO:0051607; P:defense response to virus; IEA:Compara. DR GO; GO:0045087; P:innate immune response; IEA:Compara. DR GO; GO:0045071; P:negative regulation of viral genome replication; IEA:Compara. DR GO; GO:0071651; P:positive regulation of chemokine (C-C motif) ligand 5 production; IEA:Compara. DR GO; GO:0002230; P:positive regulation of defense response to virus by host; IEA:Compara. DR GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara. DR GO; GO:0032727; P:positive regulation of interferon-alpha production; IEA:Compara. DR GO; GO:0032728; P:positive regulation of interferon-beta production; IEA:Compara. DR GO; GO:0032757; P:positive regulation of interleukin-8 production; IEA:Compara. DR GO; GO:0071660; P:positive regulation of IP-10 production; IEA:Compara. DR GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Compara. DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Compara. DR GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara. DR GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IEA:Compara. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara. DR GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Compara. DR GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Compara. DR GO; GO:1900063; P:regulation of peroxisome organization; IEA:Compara. DR InterPro; IPR026148; Mt_antiviral_sig_pro. DR PANTHER; PTHR21446; PTHR21446; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 333 AA; 34389 MW; 8AEC8828800F1773 CRC64; MSGGSLIPSP NQQALSPQPS REHQEQEPEL GGAHAANVAS VPIATYGPVS PTVSFQPLPR TALRTNLLSG VTVSALSADT SLSSSSTGSA FAKGAGDQAK AATCFSTTLT NSVTTSSVPS PRLVPVKTMS SKLPLSSKST AAMTSTVLTN TAPSKLPSNS VYAGTVPSRV PASVAKAPAN TIPPERNSKQ AKETPEGPAT KVTTGGNQTG PNSSIRSLHS GPEMSKPGVL VSQLDEPFSA CSVDLAISPS SSLVSEPNHG PEENEYSSFR IQVDESPSAD LLGSPEPLAT QQPQEEEEHC ASSMPWAKWL GATSALLAVF LAVMLYRSRR LAQ //