ID Q3U3Q8_MOUSE Unreviewed; 549 AA. AC Q3U3Q8; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 19-JAN-2010, entry version 39. DE SubName: Full=Putative uncharacterized protein; GN Name=Rela; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=NOD; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). CC -!- SIMILARITY: Contains 1 RHD (Rel-like) domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK154630; BAE32727.1; -; mRNA. DR IPI; IPI00134188; -. DR UniGene; Mm.249966; -. DR SMR; Q3U3Q8; 20-319, 191-325. DR STRING; Q3U3Q8; -. DR Ensembl; ENSMUST00000025867; ENSMUSP00000025867; ENSMUSG00000024927; Mus musculus. DR MGI; MGI:103290; Rela. DR HOVERGEN; Q3U3Q8; -. DR InParanoid; Q3U3Q8; -. DR ArrayExpress; Q3U3Q8; -. DR Bgee; Q3U3Q8; -. DR Genevestigator; Q3U3Q8; -. DR GO; GO:0005829; C:cytosol; IDA:MGI. DR GO; GO:0005667; C:transcription factor complex; IEA:Compara. DR GO; GO:0042802; F:identical protein binding; IEA:Compara. DR GO; GO:0051059; F:NF-kappaB binding; IEA:Compara. DR GO; GO:0042301; F:phosphate binding; IEA:Compara. DR GO; GO:0032403; F:protein complex binding; IEA:Compara. DR GO; GO:0019901; F:protein kinase binding; IEA:Compara. DR GO; GO:0047485; F:protein N-terminus binding; IEA:Compara. DR GO; GO:0003705; F:RNA polymerase II transcription factor acti...; IEA:Compara. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:Compara. DR GO; GO:0016563; F:transcription activator activity; TAS:MGI. DR GO; GO:0033613; F:transcription activator binding; IEA:Compara. DR GO; GO:0070491; F:transcription repressor binding; IEA:Compara. DR GO; GO:0007568; P:aging; IEA:Compara. DR GO; GO:0006916; P:anti-apoptosis; IEA:Compara. DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Compara. DR GO; GO:0001942; P:hair follicle development; IMP:MGI. DR GO; GO:0006954; P:inflammatory response; IEA:Compara. DR GO; GO:0046627; P:negative regulation of insulin receptor sig...; IEA:Compara. DR GO; GO:0042177; P:negative regulation of protein catabolic pr...; IMP:MGI. DR GO; GO:0009887; P:organ morphogenesis; IMP:MGI. DR GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Compara. DR GO; GO:0032332; P:positive regulation of chondrocyte differen...; IEA:Compara. DR GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-k...; IEA:Compara. DR GO; GO:0045084; P:positive regulation of interleukin-12 biosy...; IDA:MGI. DR GO; GO:0051092; P:positive regulation of NF-kappaB transcript...; IEA:Compara. DR GO; GO:0014040; P:positive regulation of Schwann cell differe...; IEA:Compara. DR GO; GO:0045944; P:positive regulation of transcription from R...; IEA:Compara. DR GO; GO:0043200; P:response to amino acid stimulus; IEA:Compara. DR GO; GO:0051591; P:response to cAMP; IEA:Compara. DR GO; GO:0033590; P:response to cobalamin; IEA:Compara. DR GO; GO:0042493; P:response to drug; IEA:Compara. DR GO; GO:0042542; P:response to hydrogen peroxide; IEA:Compara. DR GO; GO:0010035; P:response to inorganic substance; IEA:Compara. DR GO; GO:0032868; P:response to insulin stimulus; IEA:Compara. DR GO; GO:0070555; P:response to interleukin-1; IEA:Compara. DR GO; GO:0032496; P:response to lipopolysaccharide; IEA:Compara. DR GO; GO:0009612; P:response to mechanical stimulus; IEA:Compara. DR GO; GO:0043278; P:response to morphine; IEA:Compara. DR GO; GO:0032495; P:response to muramyl dipeptide; IDA:MGI. DR GO; GO:0032570; P:response to progesterone stimulus; IEA:Compara. DR GO; GO:0010224; P:response to UV-B; IEA:Compara. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR014756; Ig_E-set. DR InterPro; IPR002909; IPT_TIG_rcpt. DR InterPro; IPR000451; NF_Rel_dor. DR InterPro; IPR008967; p53-like_TF_DNA-bd. DR InterPro; IPR011539; RHD. DR Gene3D; G3DSA:2.60.40.10; Ig-like_fold; 1. DR Gene3D; G3DSA:2.60.40.340; RHD; 1. DR Pfam; PF00554; RHD; 1. DR PRINTS; PR00057; NFKBTNSCPFCT. DR SMART; SM00429; IPT; 1. DR PROSITE; PS01204; REL_1; 1. DR PROSITE; PS50254; REL_2; 1. PE 2: Evidence at transcript level; KW Nucleus. SQ SEQUENCE 549 AA; 60230 MW; BDF16026425258B9 CRC64; MDDLFPLIFP SEPAQASGPY VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT IKINGYTGPG TVRISLVTKD PPHRPHPHEL VGKDCRDGYY EADLCPDRSI HSFQNLGIQC VKKRDLEQAI SQRIQTNNNP FHVPIEEQRG DYDLNAVRLC FQVTVRDPAG RPLLLTPVLS HPIFDNRAPN TAELKICRVN RNSGSCLGGD EIFLLCDKVQ KEDIEVYFTG PGWEARGSFS QADVHRQVAI VFRTPPYADP SLQAPVRVSM QLRRPSDREL SEPMEFQYLP DTDDRHRIEE KRKRTYETFK SIMKKSPFNG PTEPRPPTRR IAVPTRNSTS VPKPAPQPYT FPASLSTINF DEFSPMLLPS GQISNQALAL APSSAPVLAQ TMVPSSAMVP LAQPPAPAPV LTPGPPQSLS APVPKSTQAG EGTLSEALLH LQFDADEDLG ALLGNSTDPG VFTDLASVDN SEFQQLLNQG VSMSHSTAEP MLMEYPEAMT RLVTGSQRPP DPAPTPLGTS GLPNGLSGDE DFSSIADMDF SALLSQISS //