ID RL19_BOVIN Reviewed; 196 AA. AC Q3T0W9; A5PJA9; DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot. DT 11-OCT-2005, sequence version 1. DT 24-JAN-2024, entry version 106. DE RecName: Full=Large ribosomal subunit protein eL19 {ECO:0000305}; DE AltName: Full=60S ribosomal protein L19; GN Name=RPL19; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Crossbred X Angus, and Hereford; TISSUE=Fetal pons, and Ileum; RG NIH - Mammalian Gene Collection (MGC) project; RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a CC large ribonucleoprotein complex responsible for the synthesis of CC proteins in the cell. {ECO:0000250|UniProtKB:P84098}. CC -!- SUBUNIT: Component of the large ribosomal subunit. CC {ECO:0000250|UniProtKB:P84098}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P84098}. CC -!- PTM: Citrullinated by PADI4. {ECO:0000250|UniProtKB:P84099}. CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL19 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC102223; AAI02224.1; -; mRNA. DR EMBL; BC142030; AAI42031.1; -; mRNA. DR RefSeq; NP_001035606.1; NM_001040516.1. DR PDB; 6MTD; EM; 3.30 A; R=2-181. DR PDB; 6MTE; EM; 3.40 A; R=2-181. DR PDB; 6ZVK; EM; 3.49 A; 32=2-181. DR PDB; 7A01; EM; 3.60 A; 32=2-181. DR PDB; 7NFX; EM; 3.20 A; R=2-181. DR PDB; 7NWG; EM; 3.80 A; R3=1-196. DR PDB; 7NWH; EM; 4.10 A; R=1-196. DR PDB; 7NWI; EM; 3.13 A; R=1-196. DR PDB; 7O7Y; EM; 2.20 A; BR=1-196. DR PDB; 7O7Z; EM; 2.40 A; BR=1-196. DR PDB; 7O80; EM; 2.90 A; BR=1-196. DR PDB; 7O81; EM; 3.10 A; BR=1-196. DR PDB; 7OBR; EM; 2.80 A; R=2-181. DR PDB; 7OYD; EM; 2.30 A; R=1-196. DR PDB; 7QWQ; EM; 2.83 A; R=1-196. DR PDB; 7QWR; EM; 2.90 A; R=1-196. DR PDB; 7QWS; EM; 3.40 A; R=1-196. DR PDB; 8BTK; EM; 3.50 A; BR=1-196. DR PDBsum; 6MTD; -. DR PDBsum; 6MTE; -. DR PDBsum; 6ZVK; -. DR PDBsum; 7A01; -. DR PDBsum; 7NFX; -. DR PDBsum; 7NWG; -. DR PDBsum; 7NWH; -. DR PDBsum; 7NWI; -. DR PDBsum; 7O7Y; -. DR PDBsum; 7O7Z; -. DR PDBsum; 7O80; -. DR PDBsum; 7O81; -. DR PDBsum; 7OBR; -. DR PDBsum; 7OYD; -. DR PDBsum; 7QWQ; -. DR PDBsum; 7QWR; -. DR PDBsum; 7QWS; -. DR PDBsum; 8BTK; -. DR AlphaFoldDB; Q3T0W9; -. DR EMDB; EMD-12303; -. DR EMDB; EMD-12631; -. DR EMDB; EMD-12632; -. DR EMDB; EMD-12633; -. DR EMDB; EMD-12756; -. DR EMDB; EMD-12757; -. DR EMDB; EMD-12758; -. DR EMDB; EMD-12759; -. DR EMDB; EMD-12801; -. DR EMDB; EMD-13114; -. DR EMDB; EMD-14191; -. DR EMDB; EMD-14192; -. DR EMDB; EMD-14193; -. DR SMR; Q3T0W9; -. DR STRING; 9913.ENSBTAP00000002666; -. DR PaxDb; 9913-ENSBTAP00000002666; -. DR PeptideAtlas; Q3T0W9; -. DR Ensembl; ENSBTAT00000002666.5; ENSBTAP00000002666.5; ENSBTAG00000002060.5. DR GeneID; 510615; -. DR VEuPathDB; HostDB:ENSBTAG00000002060; -. DR VGNC; VGNC:49956; RPL19. DR eggNOG; KOG1696; Eukaryota. DR GeneTree; ENSGT00390000012628; -. DR HOGENOM; CLU_083919_0_1_1; -. DR InParanoid; Q3T0W9; -. DR OMA; NRVWIDP; -. DR OrthoDB; 5483247at2759; -. DR Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression. DR Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane. DR Reactome; R-BTA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol. DR Reactome; R-BTA-72689; Formation of a pool of free 40S subunits. DR Reactome; R-BTA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit. DR Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC). DR Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). DR Proteomes; UP000009136; Chromosome 19. DR Bgee; ENSBTAG00000002060; Expressed in adenohypophysis and 107 other cell types or tissues. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. DR GO; GO:0003723; F:RNA binding; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IEA:InterPro. DR CDD; cd01417; Ribosomal_L19e_E; 1. DR Gene3D; 1.10.1200.240; -; 1. DR Gene3D; 1.10.1650.10; -; 1. DR HAMAP; MF_01475; Ribosomal_eL19; 1. DR InterPro; IPR035970; 60S_ribosomal_eL19_sf. DR InterPro; IPR039547; Ribosomal_eL19. DR InterPro; IPR023638; Ribosomal_eL19_CS. DR InterPro; IPR000196; Ribosomal_eL19_dom. DR InterPro; IPR015972; Ribosomal_eL19_dom1. DR InterPro; IPR033935; Ribosomal_eL19_euk. DR PANTHER; PTHR10722; 60S RIBOSOMAL PROTEIN L19; 1. DR PANTHER; PTHR10722:SF0; 60S RIBOSOMAL PROTEIN L19; 1. DR Pfam; PF01280; Ribosomal_L19e; 1. DR SMART; SM01416; Ribosomal_L19e; 1. DR SUPFAM; SSF48140; Ribosomal protein L19 (L19e); 1. DR PROSITE; PS00526; RIBOSOMAL_L19E; 1. PE 1: Evidence at protein level; KW 3D-structure; Citrullination; Cytoplasm; Isopeptide bond; Phosphoprotein; KW Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation. FT CHAIN 1..196 FT /note="Large ribosomal subunit protein eL19" FT /id="PRO_0000230304" FT REGION 157..176 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT MOD_RES 5 FT /note="Citrulline" FT /evidence="ECO:0000250|UniProtKB:P84099" FT MOD_RES 13 FT /note="Phosphoserine" FT /evidence="ECO:0000250|UniProtKB:P84098" FT MOD_RES 16 FT /note="Citrulline" FT /evidence="ECO:0000250|UniProtKB:P84099" FT MOD_RES 38 FT /note="Citrulline" FT /evidence="ECO:0000250|UniProtKB:P84099" FT MOD_RES 164 FT /note="Phosphoserine" FT /evidence="ECO:0000250|UniProtKB:P84098" FT MOD_RES 187 FT /note="Phosphothreonine" FT /evidence="ECO:0000250|UniProtKB:P84098" FT CROSSLNK 181 FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with FT G-Cter in SUMO1)" FT /evidence="ECO:0000250|UniProtKB:P84098" SQ SEQUENCE 196 AA; 23466 MW; 4AF506393E526216 CRC64; MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK //