ID   Q3KP16_MOUSE            Unreviewed;       126 AA.
AC   Q3KP16;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   16-APR-2014, entry version 59.
DE   RecName: Full=P2X purinoceptor;
GN   Name=P2rx2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=PCR rescued clones;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA   Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA   Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA   Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA   Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA   Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA   Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA   Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA   Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA   Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA   Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA   Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA   Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA   Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA   Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA   Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA   Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA   Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA   Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the P2X receptor family.
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DR   EMBL; BC106963; AAI06964.1; -; mRNA.
DR   UniGene; Mm.55948; -.
DR   MGI; MGI:2665170; P2rx2.
DR   InParanoid; Q3KP16; -.
DR   Bgee; Q3KP16; -.
DR   Genevestigator; Q3KP16; -.
DR   GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR   GO; GO:0043197; C:dendritic spine; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:Ensembl.
DR   GO; GO:0005622; C:intracellular; IDA:MGI.
DR   GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IDA:MGI.
DR   GO; GO:0014069; C:postsynaptic density; IEA:Ensembl.
DR   GO; GO:0042734; C:presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0043235; C:receptor complex; ISO:MGI.
DR   GO; GO:0043195; C:terminal bouton; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0046870; F:cadmium ion binding; IEA:Ensembl.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IDA:MGI.
DR   GO; GO:0045340; F:mercury ion binding; IEA:Ensembl.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IMP:MGI.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0003029; P:detection of hypoxic conditions in blood by carotid body chemoreceptor signaling; IMP:MGI.
DR   GO; GO:0007528; P:neuromuscular junction development; IMP:MGI.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; IMP:MGI.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; IBA:GOC.
DR   GO; GO:0033198; P:response to ATP; IMP:MGI.
DR   GO; GO:0009743; P:response to carbohydrate; IMP:MGI.
DR   GO; GO:0001666; P:response to hypoxia; IMP:MGI.
DR   GO; GO:0010033; P:response to organic substance; IMP:MGI.
DR   GO; GO:0050909; P:sensory perception of taste; IGI:MGI.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IMP:MGI.
DR   GO; GO:0007268; P:synaptic transmission; IMP:MGI.
DR   GO; GO:0014832; P:urinary bladder smooth muscle contraction; IMP:MGI.
DR   Gene3D; 2.60.490.10; -; 1.
DR   InterPro; IPR003045; P2X2_purnocptor.
DR   InterPro; IPR027309; P2X_extracellular_dom.
DR   InterPro; IPR001429; P2X_purnocptor.
DR   PANTHER; PTHR10125; PTHR10125; 1.
DR   PANTHER; PTHR10125:SF4; PTHR10125:SF4; 1.
DR   Pfam; PF00864; P2X_receptor; 1.
DR   PRINTS; PR01307; P2XRECEPTOR.
PE   2: Evidence at transcript level;
KW   Ion channel; Ion transport; Receptor; Transport.
SQ   SEQUENCE   126 AA;  14021 MW;  A9783F6CFAE916D6 CRC64;
     MSEHKVWDVE EYVKPPEGGS VVSIITRIEV TPSQTLGTCP ESMRVHSSTC HLDDDCVAGQ
     LDMQGNGIRT GRCVPYYHGD SKTCEVSAWC PVEDGTSENH FLGKMAPNFT ILIKNSIHYP
     KFKFSK
//