ID   Q3KP16_MOUSE            Unreviewed;       126 AA.
AC   Q3KP16;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   03-OCT-2012, entry version 45.
DE   RecName: Full=P2X purinoceptor;
GN   Name=P2rx2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=PCR rescued clones;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA   Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA   Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA   Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA   Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA   Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA   Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA   Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA   Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA   Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA   Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA   Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA   Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA   Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA   Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA   Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA   Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA   Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA   Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Homo- or heteropolymers (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the P2X receptor family.
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DR   EMBL; BC106963; AAI06964.1; -; mRNA.
DR   IPI; IPI00944756; -.
DR   UniGene; Mm.55948; -.
DR   STRING; Q3KP16; -.
DR   InParanoid; Q3KP16; -.
DR   OrthoDB; EOG44QT14; -.
DR   ArrayExpress; Q3KP16; -.
DR   Bgee; Q3KP16; -.
DR   Genevestigator; Q3KP16; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005624; C:membrane fraction; IEA:Compara.
DR   GO; GO:0043025; C:neuronal cell body; IEA:Compara.
DR   GO; GO:0005886; C:plasma membrane; IEA:Compara.
DR   GO; GO:0014069; C:postsynaptic density; IEA:Compara.
DR   GO; GO:0042734; C:presynaptic membrane; IEA:Compara.
DR   GO; GO:0043195; C:terminal button; IEA:Compara.
DR   GO; GO:0005524; F:ATP binding; IEA:Compara.
DR   GO; GO:0046870; F:cadmium ion binding; IEA:Compara.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:Compara.
DR   GO; GO:0005507; F:copper ion binding; IEA:Compara.
DR   GO; GO:0008144; F:drug binding; IEA:Compara.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IEA:Compara.
DR   GO; GO:0045340; F:mercury ion binding; IEA:Compara.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Compara.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Compara.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Compara.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Compara.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Compara.
DR   GO; GO:0019228; P:regulation of action potential in neuron; IEA:Compara.
DR   InterPro; IPR003045; P2X2_purnocptor.
DR   InterPro; IPR001429; P2X_purnocptor.
DR   PANTHER; PTHR10125; PTHR10125; 1.
DR   PANTHER; PTHR10125:SF4; PTHR10125:SF4; 1.
DR   Pfam; PF00864; P2X_receptor; 1.
DR   PRINTS; PR01307; P2XRECEPTOR.
PE   2: Evidence at transcript level;
KW   Ion transport; Ionic channel; Receptor; Transmembrane; Transport.
SQ   SEQUENCE   126 AA;  14021 MW;  A9783F6CFAE916D6 CRC64;
     MSEHKVWDVE EYVKPPEGGS VVSIITRIEV TPSQTLGTCP ESMRVHSSTC HLDDDCVAGQ
     LDMQGNGIRT GRCVPYYHGD SKTCEVSAWC PVEDGTSENH FLGKMAPNFT ILIKNSIHYP
     KFKFSK
//