ID UBIA_BURP1 Reviewed; 287 AA. AC Q3JNX1; DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot. DT 28-NOV-2006, sequence version 2. DT 19-FEB-2014, entry version 54. DE RecName: Full=4-hydroxybenzoate octaprenyltransferase; DE EC=2.5.1.-; DE AltName: Full=4-HB polyprenyltransferase; GN Name=ubiA; OrderedLocusNames=BURPS1710b_3361; OS Burkholderia pseudomallei (strain 1710b). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Burkholderia; pseudomallei group. OX NCBI_TaxID=320372; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=1710b; RA Woods D.E., Nierman W.C.; RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Synthesis of 3-octaprenyl-4-hydroxybenzoate (By CC similarity). CC -!- CATALYTIC ACTIVITY: 4-hydroxybenzoate + farnesylfarnesylgeraniol = CC 3-octaprenyl-4-hydroxybenzoate. CC -!- COFACTOR: Magnesium (By similarity). CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane CC protein (By similarity). CC -!- SIMILARITY: Belongs to the UbiA prenyltransferase family. CC -!- SEQUENCE CAUTION: CC Sequence=ABA47892.1; Type=Erroneous initiation; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000124; ABA47892.1; ALT_INIT; Genomic_DNA. DR RefSeq; YP_334732.2; NC_007434.1. DR STRING; 320372.BURPS1710b_3361; -. DR EnsemblBacteria; ABA47892; ABA47892; BURPS1710b_3361. DR GeneID; 3690328; -. DR KEGG; bpm:BURPS1710b_3361; -. DR PATRIC; 19239296; VBIBurPse115837_3498. DR eggNOG; COG0382; -. DR HOGENOM; HOG000003696; -. DR KO; K03179; -. DR OrthoDB; EOG680X3B; -. DR ProtClustDB; PRK12848; -. DR BioCyc; BPSE320372:GBYB-3361-MONOMER; -. DR UniPathway; UPA00232; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004659; F:prenyltransferase activity; IEA:InterPro. DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway. DR HAMAP; MF_01635; UbiA; 1. DR InterPro; IPR006370; HB_polyprenyl-transferase. DR InterPro; IPR000537; UbiA_prenyltransferase. DR Pfam; PF01040; UbiA; 1. DR TIGRFAMs; TIGR01474; ubiA_proteo; 1. DR PROSITE; PS00943; UBIA; 1. PE 3: Inferred from homology; KW Cell inner membrane; Cell membrane; Complete proteome; Magnesium; KW Membrane; Transferase; Transmembrane; Transmembrane helix; KW Ubiquinone biosynthesis. FT CHAIN 1 287 4-hydroxybenzoate octaprenyltransferase. FT /FTId=PRO_0000262784. FT TRANSMEM 92 112 Helical; (Potential). FT TRANSMEM 133 153 Helical; (Potential). FT TRANSMEM 158 178 Helical; (Potential). FT TRANSMEM 207 227 Helical; (Potential). FT TRANSMEM 232 252 Helical; (Potential). FT TRANSMEM 266 286 Helical; (Potential). SQ SEQUENCE 287 AA; 31688 MW; DD14493085F58D33 CRC64; MLARFPLYLR LIRMDKPIGS LLLLWPTLNA LWIASDGHPA PSLVVIFALG TLLMRSAGCA INDYADRDFD RHVKRTAERP LTSGKIRAWE AIAIAVGLAL VSFLLILPLN GLTKELSVVA VFVAATYPFM KRFFAIPQAY LGIAFGFGIP MAFAAVQDTV PMIAWAMLAA NVFWSVAYDT AYAMVDRDDD LKIGMRTSAI TFGRHDVLAI MLCYAAMLGI YVWLGAALHF GWPYWAGWAA AAGCSIYHYT LIKDRERMAC FAAFRHNNWL GGVLFAGIAA HYALAVR //