ID   TGA3_ARATH     STANDARD;      PRT;   384 AA.
AC   Q39234; Q8LBG4; Q9LM52;
DT   29-MAR-2004 (Rel. 43, Created)
DT   29-MAR-2004 (Rel. 43, Last sequence update)
DT   13-SEP-2005 (Rel. 48, Last annotation update)
DE   Transcription factor TGA3 (AtbZIP22).
GN   Name=TGA3; Synonyms=BZIP22; OrderedLocusNames=At1g22070;
GN   ORFNames=F2E2.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE, AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia;
RX   MEDLINE=94272006; PubMed=8003690;
RA   Miao Z.-H., Liu X., Lam E.;
RT   "TGA3 is a distinct member of the TGA family of bZIP transcription
RT   factors in Arabidopsis thaliana.";
RL   Plant Mol. Biol. 25:1-11(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   MEDLINE=21016719; PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   DNA-BINDING.
RX   PubMed=7479010;
RA   Lam E., Lam Y.K.;
RT   "Binding site requirements and differential representation of TGF
RT   factors in nuclear ASF-1 activity.";
RL   Nucleic Acids Res. 23:3778-3785(1995).
RN   [5]
RP   TISSUE SPECIFICITY.
RX   PubMed=8628224; DOI=10.1007/s004380050072;
RA   de Pater S., Pham K., Memelink J., Kijne J.;
RT   "Binding specificity and tissue-specific expression pattern of the
RT   Arabidopsis bZIP transcription factor TGA2.";
RL   Mol. Gen. Genet. 250:237-239(1996).
RN   [6]
RP   INTERACTION WITH NPR1.
RX   PubMed=10659709;
RA   Zhou J.-M., Trifa Y., Silva H., Pontier D., Lam E., Shah J.,
RA   Klessig D.F.;
RT   "NPR1 differentially interacts with members of the TGA/OBF family of
RT   transcription factors that bind an element of the PR-1 gene required
RT   for induction by salicylic acid.";
RL   Mol. Plant Microbe Interact. 13:191-202(2000).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11906833; DOI=10.1016/S1360-1385(01)02223-3;
RA   Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J.,
RA   Tiedemann J., Kroj T., Parcy F.;
RT   "bZIP transcription factors in Arabidopsis.";
RL   Trends Plant Sci. 7:106-111(2002).
RN   [8]
RP   FUNCTION.
RX   PubMed=12897257; DOI=10.1105/tpc.012211;
RA   Johnson C., Boden E., Arias J.;
RT   "Salicylic acid and NPR1 induce the recruitment of trans-activating
RT   TGA factors to a defense gene promoter in Arabidopsis.";
RL   Plant Cell 15:1846-1858(2003).
CC   -!- FUNCTION: Transcriptional activator that binds specifically to the
CC       DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1
CC       motif of the cauliflower mosaic virus 35S promoter. Binding to the
CC       as-1-like cis elements mediate auxin- and salicylic acid-inducible
CC       transcription. Required to induce the systemic aquired resistance
CC       (SAR) via the regulation of pathogenesis-related genes expression.
CC       Binding to the as-1 element of PR-1 promoter is salicylic acid-
CC       inducible and mediated by NPR1. Could also bind to the Hex-motif
CC       (5'-TGACGTGG-3') another cis-acting element found in plant histone
CC       promoters.
CC   -!- SUBUNIT: Binds DNA as a dimer. Interacts with NPR1.
CC   -!- SUBCELLULAR LOCATION: Nuclear.
CC   -!- TISSUE SPECIFICITY: Expressed in the whole plant.
CC   -!- SIMILARITY: Belongs to the bZIP family.
CC   -!- SIMILARITY: Contains 1 bZIP domain.
CC   -!- CAUTION: Ref.2 sequence differs from that shown due to erroneous
CC       gene model prediction.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L10209; AAA32873.1; -; mRNA.
DR   EMBL; AC069252; AAF86550.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AY087225; AAM64781.1; ALT_INIT; mRNA.
DR   PIR; F86353; F86353.
DR   PIR; S46523; S46523.
DR   HSSP; P03069; 1YSA.
DR   TRANSFAC; T02796; -.
DR   GeneFarm; 2993; 292.
DR   InterPro; IPR011700; bZIP_2.
DR   InterPro; IPR004827; TF_bZIP.
DR   Pfam; PF07716; bZIP_2; 1.
DR   SMART; SM00338; BRLZ; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
KW   Activator; Coiled coil; DNA-binding; Hypersensitive response;
KW   Nuclear protein; Plant defense; Transcription;
KW   Transcription regulation.
FT   DOMAIN      124    138       Leucine-zipper.
FT   DNA_BIND     98    117       Basic motif.
FT   COILED       98    151       Potential.
FT   COILED      267    296       Potential.
FT   CONFLICT     58     58       V -> F (in Ref. 3).
SQ   SEQUENCE   384 AA;  43755 MW;  48F965F62A2980A9 CRC64;
     MEMMSSSSST TQVVSFRDMG MYEPFQQLSG WESPFKSDIN NITSNQNNNQ SSSTTLEVDA
     RPEADDNNRV NYTSVYNNSL EAEPSSNNDQ DEDRINDKMK RRLAQNREAA RKSRLRKKAH
     VQQLEESRLK LSQLEQELVR ARQQGLCVRN SSDTSYLGPA GNMNSGIAAF EMEYTHWLEE
     QNRRVSEIRT ALQAHIGDIE LKMLVDSCLN HYANLFRMKA DAAKADVFFL MSGMWRTSTE
     RFFQWIGGFR PSELLNVVMP YVEPLTDQQL LEVRNLQQSS QQAEEALSQG LDKLQQGLVE
     SIAIQIKVVE SVNHGAPMAS AMENLQALES FVNQADHLRQ QTLQQMSKIL TTRQAARGLL
     ALGEYFHRLR ALSSLWAARP REHT
//