ID DFB30_RAT Reviewed; 75 AA. AC Q32ZG2; DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot. DT 06-DEC-2005, sequence version 1. DT 04-NOV-2008, entry version 17. DE RecName: Full=Beta-defensin 30; DE Short=BD-30; DE AltName: Full=Defensin, beta 30; DE Flags: Precursor; GN Name=Defb30; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX PubMed=16033865; DOI=10.1152/physiolgenomics.00104.2005; RA Patil A.A., Cai Y., Sang Y., Blecha F., Zhang G.; RT "Cross-species analysis of the mammalian beta-defensin gene family: RT presence of syntenic gene clusters and preferential expression in the RT male reproductive tract."; RL Physiol. Genomics 23:5-17(2005). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA]. RC STRAIN=Wistar; TISSUE=Epididymis; RX PubMed=16457734; DOI=10.1186/1477-7827-4-7; RA Yenugu S., Chintalgattu V., Wingard C.J., Radhakrishnan Y., RA French F.S., Hall S.H.; RT "Identification, cloning and functional characterization of novel RT beta-defensins in the rat (Rattus norvegicus)."; RL Reprod. Biol. Endocrinol. 4:7-7(2006). CC -!- FUNCTION: Has antibacterial activity (By similarity). CC -!- SUBCELLULAR LOCATION: Secreted (By similarity). CC -!- SIMILARITY: Belongs to the beta-defensin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY621361; AAT51900.1; -; mRNA. DR EMBL; AY600146; AAU04550.1; -; mRNA. DR RefSeq; NP_001032620.1; -. DR UniGene; Rn.198992; -. DR Ensembl; ENSRNOG00000038758; Rattus norvegicus. DR GeneID; 641656; -. DR KEGG; rno:641656; -. DR RGD; 1559641; Defb30. DR HOVERGEN; Q32ZG2; -. DR NextBio; 714843; -. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW. DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW. PE 3: Inferred from homology; KW Antibiotic; Antimicrobial; Defensin; Secreted; Signal. FT SIGNAL 1 22 Potential. FT CHAIN 23 75 Beta-defensin 30. FT /FTId=PRO_0000352711. FT DISULFID 35 62 By similarity. FT DISULFID 42 56 By similarity. FT DISULFID 46 63 By similarity. SQ SEQUENCE 75 AA; 8708 MW; 84600A03982EEC1C CRC64; MGSLQLILVL FVLLSDVPPV RSGVNMYIRQ IYDTCWKLKG HCRNVCGKKE IFHIFCGTQF LCCIERKEMP VLFVK //