ID CR021_HUMAN Reviewed; 220 AA. AC Q32NC0; Q6GW03; Q9BXV6; Q9BXW2; DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot. DT 06-DEC-2005, sequence version 1. DT 22-JAN-2014, entry version 70. DE RecName: Full=UPF0711 protein C18orf21; DE AltName: Full=HBV X-transactivated gene 13 protein; DE AltName: Full=HBV XAg-transactivated protein 13; GN Name=C18orf21; Synonyms=XTP13; ORFNames=PNAS-124, PNAS-131; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Colon; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-220. RC TISSUE=Promyelocytic leukemia; RA Yu W.-Q., Sun B.-Z., Chai Y.-B., Zhu F., Liu X.-S., Li Z., Lu F., RA Yan W., Yang H., Zhao Z.-L.; RT "Human acute promyelocytic leukemia cell line NB4's RT apoptosis/differentiation related genes."; RL Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [MRNA] OF 89-220, AND VARIANT ALA-132. RA Cheng J., Liu Y., Hong Y., Wang J.-J., Yang Q.; RT "Screening and cloning of the target genes transactivated by hepatitis RT B virus X protein by microarray assay."; RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. RN [4] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-126; THR-130 AND RP THR-139, AND MASS SPECTROMETRY. RC TISSUE=Cervix carcinoma; RX PubMed=18669648; DOI=10.1073/pnas.0805139105; RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., RA Elledge S.J., Gygi S.P.; RT "A quantitative atlas of mitotic phosphorylation."; RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). CC -!- SIMILARITY: Belongs to the UPF0711 family. CC -!- SEQUENCE CAUTION: CC Sequence=AAK07541.1; Type=Erroneous initiation; CC Sequence=AAK07547.1; Type=Frameshift; Positions=216; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC108730; AAI08731.1; -; mRNA. DR EMBL; BC119765; AAI19766.1; -; mRNA. DR EMBL; BC119766; AAI19767.1; -; mRNA. DR EMBL; AF277182; AAK07541.1; ALT_INIT; mRNA. DR EMBL; AF277189; AAK07547.1; ALT_SEQ; mRNA. DR EMBL; AY631401; AAT51696.1; -; mRNA. DR RefSeq; NP_001188403.1; NM_001201474.1. DR RefSeq; NP_001188404.1; NM_001201475.1. DR RefSeq; NP_113634.3; NM_031446.4. DR UniGene; Hs.37883; -. DR ProteinModelPortal; Q32NC0; -. DR STRING; 9606.ENSP00000329492; -. DR PhosphoSite; Q32NC0; -. DR DMDM; 121942208; -. DR PaxDb; Q32NC0; -. DR PRIDE; Q32NC0; -. DR DNASU; 83608; -. DR Ensembl; ENST00000592875; ENSP00000465517; ENSG00000141428. DR GeneID; 83608; -. DR KEGG; hsa:83608; -. DR UCSC; uc002kzc.3; human. DR CTD; 83608; -. DR GeneCards; GC18P033552; -. DR H-InvDB; HIX0014403; -. DR H-InvDB; HIX0136846; -. DR HGNC; HGNC:28802; C18orf21. DR neXtProt; NX_Q32NC0; -. DR PharmGKB; PA134888949; -. DR eggNOG; NOG39164; -. DR HOGENOM; HOG000293223; -. DR HOVERGEN; HBG081337; -. DR InParanoid; Q32NC0; -. DR OMA; HHGKSRS; -. DR OrthoDB; EOG7FBRKD; -. DR GenomeRNAi; 83608; -. DR NextBio; 72563; -. DR ArrayExpress; Q32NC0; -. DR Bgee; Q32NC0; -. DR CleanEx; HS_C18orf21; -. DR Genevestigator; Q32NC0; -. PE 1: Evidence at protein level; KW Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. FT CHAIN 1 220 UPF0711 protein C18orf21. FT /FTId=PRO_0000279448. FT MOD_RES 126 126 Phosphoserine. FT MOD_RES 130 130 Phosphothreonine. FT MOD_RES 139 139 Phosphothreonine. FT VARIANT 132 132 T -> A (in dbSNP:rs2276314). FT /FTId=VAR_030903. FT CONFLICT 212 212 S -> F (in Ref. 2; AAK07541). SQ SEQUENCE 220 AA; 24827 MW; 3BB72C83F47F14EF CRC64; MRQKHYLEAA ARGLHDSCPG QARYLLWAYT SSHDDKSTFE ETCPYCFQLL VLDNSRVRLK PKARLTPKIQ KLLNREARNY TLSFKEAKMV KKFKDSKSVL LITCKTCNRT VKHHGKSRSF VSTLKSNPAT PTSKLSLKTP ERRTANPNHD MSGSKGKSPA SVFRTPTSGQ SVSTCSSKNT SKTKKHFSQL KMLLSQNESQ KIPKVDFRNF LSSLKGGLLK //