ID CR021_HUMAN Reviewed; 220 AA. AC Q32NC0; Q6GW03; Q9BXV6; Q9BXW2; DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot. DT 06-DEC-2005, sequence version 1. DT 13-NOV-2007, entry version 21. DE Uncharacterized protein C18orf21 (HBV X-transactivated gene 13 DE protein). GN Name=C18orf21; Synonyms=XTP13; ORFNames=PNAS-124, PNAS-131; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Colon; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-220. RC TISSUE=Promyelocytic leukemia; RA Yu W.-Q., Sun B.-Z., Chai Y.-B., Zhu F., Liu X.-S., Li Z., Lu F., RA Yan W., Yang H., Zhao Z.-L.; RT "Human acute promyelocytic leukemia cell line NB4's RT apoptosis/differentiation related genes."; RL Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [MRNA] OF 89-220, AND VARIANT ALA-132. RA Cheng J., Liu Y., Hong Y., Wang J.-J., Yang Q.; RT "Screening and cloning of the target genes transactivated by hepatitis RT B virus X protein by microarray assay."; RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. RN [4] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-126 AND THR-130, AND RP MASS SPECTROMETRY. RC TISSUE=Epithelium; RX PubMed=16964243; DOI=10.1038/nbt1240; RA Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; RT "A probability-based approach for high-throughput protein RT phosphorylation analysis and site localization."; RL Nat. Biotechnol. 24:1285-1292(2006). RN [5] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117 AND SER-122, AND RP MASS SPECTROMETRY. RC TISSUE=Epithelium; RX PubMed=17924679; DOI=10.1021/pr070152u; RA Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; RT "Improved titanium dioxide enrichment of phosphopeptides from HeLa RT cells and high confident phosphopeptide identification by cross- RT validation of MS/MS and MS/MS/MS spectra."; RL J. Proteome Res. 0:0-0(2007). CC -!- SEQUENCE CAUTION: CC Sequence=AAK07547.1; Type=Frameshift; Positions=216; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC108730; AAI08731.1; -; mRNA. DR EMBL; BC119765; AAI19766.1; -; mRNA. DR EMBL; BC119766; AAI19767.1; -; mRNA. DR EMBL; AF277182; AAK07541.1; ALT_INIT; mRNA. DR EMBL; AF277189; AAK07547.1; ALT_SEQ; mRNA. DR EMBL; AY631401; AAT51696.1; -; mRNA. DR RefSeq; NP_113634.3; -. DR UniGene; Hs.37883; -. DR Ensembl; ENSG00000141428; Homo sapiens. DR GeneID; 83608; -. DR KEGG; hsa:83608; -. DR HGNC; HGNC:28802; C18orf21. DR PharmGKB; PA134888949; -. DR ArrayExpress; Q32NC0; -. DR CleanEx; HS_C18orf21; -. PE 1: Evidence at protein level; KW Phosphoprotein; Polymorphism. FT CHAIN 1 220 Uncharacterized protein C18orf21. FT /FTId=PRO_0000279448. FT MOD_RES 117 117 Phosphoserine. FT MOD_RES 122 122 Phosphoserine. FT MOD_RES 126 126 Phosphoserine. FT MOD_RES 130 130 Phosphothreonine. FT VARIANT 132 132 T -> A (in dbSNP:rs2276314). FT /FTId=VAR_030903. FT CONFLICT 212 212 S -> F (in Ref. 2; AAK07541). SQ SEQUENCE 220 AA; 24827 MW; 3BB72C83F47F14EF CRC64; MRQKHYLEAA ARGLHDSCPG QARYLLWAYT SSHDDKSTFE ETCPYCFQLL VLDNSRVRLK PKARLTPKIQ KLLNREARNY TLSFKEAKMV KKFKDSKSVL LITCKTCNRT VKHHGKSRSF VSTLKSNPAT PTSKLSLKTP ERRTANPNHD MSGSKGKSPA SVFRTPTSGQ SVSTCSSKNT SKTKKHFSQL KMLLSQNESQ KIPKVDFRNF LSSLKGGLLK //