ID Q2TPL4_9RICK Unreviewed; 290 AA. AC Q2TPL4; DT 24-JAN-2006, integrated into UniProtKB/TrEMBL. DT 24-JAN-2006, sequence version 1. DT 16-DEC-2008, entry version 16. DE RecName: Full=60 kDa chaperonin; DE Flags: Fragment; GN Name=groEL; OS Wolbachia endosymbiont of Drosophila simulans. OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; OC Rickettsiaceae; Wolbachieae; Wolbachia. OX NCBI_TaxID=77038; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=16339946; DOI=10.1099/mic.0.28313-0; RA Casiraghi M., Bordenstein S.R., Baldo L., Lo N., Beninati T., RA Wernegreen J.J., Werren J.H., Bandi C.; RT "Phylogeny of Wolbachia pipientis based on gltA, groEL and ftsZ gene RT sequences: clustering of arthropod and nematode symbionts in the F RT supergroup, and evidence for further diversity in the Wolbachia RT tree."; RL Microbiology 151:4015-4022(2005). RN [2] RP NUCLEOTIDE SEQUENCE. RX PubMed=16267140; DOI=10.1093/molbev/msj049; RA Baldo L., Bordenstein S., Wernegreen J.J., Werren J.H.; RT "Widespread recombination throughout Wolbachia genomes."; RL Mol. Biol. Evol. 23:437-449(2006). CC -!- FUNCTION: Prevents misfolding and promotes the refolding and CC proper assembly of unfolded polypeptides generated under stress CC conditions (By similarity). CC -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of CC 7 subunits (By similarity). CC -!- SIMILARITY: Belongs to the chaperonin (HSP60) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY714800; AAW52263.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro. DR GO; GO:0006457; P:protein folding; IEA:InterPro. DR InterPro; IPR001844; Chaprnin_Cpn60. DR InterPro; IPR002423; Cpn60/TCP-1. DR PANTHER; PTHR11353; Cpn60/TCP-1; 1. DR Pfam; PF00118; Cpn60_TCP1; 1. DR PRINTS; PR00298; CHAPERONIN60. DR PRINTS; PR00304; TCOMPLEXTCP1. DR ProDom; PD002202; Rota_NSP4; 1. PE 3: Inferred from homology; FT NON_TER 1 1 FT NON_TER 290 290 SQ SEQUENCE 290 AA; 30992 MW; E228A799D31EDCDD CRC64; VAAMVDSTVG ATAGPRGNTI GISKPYGGPE VTKDGYKVMK GIKPEKPLHS AIVSTIAQSA SQCNDKVGDG TTTCSILTSN MIMEASKSIA AGNDRICIKN GIQKAKDVIL KEITSMSRTI SLEKMDEVAQ VAIISANGDK DIGNSIADAV KKVGKEGVIT VEESKGSKEL EVELTTGMQF DRGYLSPYFV TNNEKMSVEL DDPYLLITEK KLNIIQPLLP ILEAIFKSGK PLFIIAEDVE GEALSTLVIN KLRGLKVAAV KAPGFGDRRK EMLEDIAALT GAKYVIKDEL //