ID Q2RVL0_RHORT Unreviewed; 753 AA. AC Q2RVL0; DT 24-JAN-2006, integrated into UniProtKB/TrEMBL. DT 24-JAN-2006, sequence version 1. DT 22-FEB-2023, entry version 89. DE SubName: Full=Multi-sensor signal transduction histidine kinase {ECO:0000313|EMBL:ABC21835.1}; DE EC=2.7.3.- {ECO:0000313|EMBL:ABC21835.1}; GN ORFNames=Rru_A1034 {ECO:0000313|EMBL:ABC21835.1}; OS Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / OS NCIMB 8255 / S1). OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales; OC Rhodospirillaceae; Rhodospirillum. OX NCBI_TaxID=269796 {ECO:0000313|EMBL:ABC21835.1, ECO:0000313|Proteomes:UP000001929}; RN [1] {ECO:0000313|EMBL:ABC21835.1, ECO:0000313|Proteomes:UP000001929} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1 RC {ECO:0000313|Proteomes:UP000001929}; RX PubMed=21886856; DOI=10.4056/sigs.1804360; RA Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K., RA Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., RA Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C., RA Mavromatis K., Richardson P., Rohde M., Goker M., Klenk H.P., Zhang Y., RA Roberts G.P., Reslewic S., Schwartz D.C.; RT "Complete genome sequence of Rhodospirillum rubrum type strain (S1)."; RL Stand. Genomic Sci. 4:293-302(2011). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000230; ABC21835.1; -; Genomic_DNA. DR RefSeq; WP_011388789.1; NC_007643.1. DR RefSeq; YP_426122.1; NC_007643.1. DR AlphaFoldDB; Q2RVL0; -. DR STRING; 269796.Rru_A1034; -. DR EnsemblBacteria; ABC21835; ABC21835; Rru_A1034. DR KEGG; rru:Rru_A1034; -. DR PATRIC; fig|269796.9.peg.1089; -. DR eggNOG; COG5002; Bacteria. DR HOGENOM; CLU_369544_0_0_5; -. DR OMA; FRIMAVQ; -. DR PhylomeDB; Q2RVL0; -. DR Proteomes; UP000001929; Chromosome. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW. DR CDD; cd00130; PAS; 1. DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1. DR Gene3D; 3.30.450.20; PAS domain; 1. DR InterPro; IPR003594; HATPase_C. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR000014; PAS. DR InterPro; IPR035965; PAS-like_dom_sf. DR PANTHER; PTHR43047:SF64; HISTIDINE KINASE; 1. DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1. DR Pfam; PF02518; HATPase_c; 1. DR Pfam; PF13426; PAS_9; 1. DR SMART; SM00091; PAS; 1. DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1. DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1. DR TIGRFAMs; TIGR00229; sensory_box; 1. DR PROSITE; PS50109; HIS_KIN; 1. DR PROSITE; PS50112; PAS; 1. PE 4: Predicted; KW Kinase {ECO:0000313|EMBL:ABC21835.1}; Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000001929}; KW Transferase {ECO:0000313|EMBL:ABC21835.1}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 312..334 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 346..368 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 399..444 FT /note="PAS" FT /evidence="ECO:0000259|PROSITE:PS50112" FT DOMAIN 530..753 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" FT REGION 10..289 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 452..475 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 68..92 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 113..134 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 174..189 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 753 AA; 78740 MW; 1A9338FD952F07EF CRC64; MIPIFKAWAA RKRSSEPTAG QSEFDLADPF VAFSDSDSAP PSAEPPSFGP PAAALPPVLT KGDGEGTEDP LVAWRAEESP RRRTDPPPAE RRHDPFLGGS FGGAGDAVAE EVSRALSWDE AEKTGGRVGE GEADTLDPVD EDDLYEPLSA TPRDPDAPRI ARDPPSPLGV DPLEAPRREA EDHREFSIPR SEPLAPFLLP PLPEDPLATS PSREGRPPRQ GVDKSDDPAA MAPLAAAAPV ERPSGQTGRR EPPLADIADA SDSEPPEEED RADEQQASLG PGLGEGAAHG MPAFLAEPAS ARSEARTRLD PVACGLLGLM VSLGPLGVAA GTVLATGRMP TDRWTLAAAG GLAGLFLVCA GLAAWGIWRH LGGRITRLSA QIEATDQRGR FLGRQARAAK AYLSGVLDGA PLAIVTLDGR GTIIGLNPAA EALFGYPLPR AVGRPLSLLT AAGEDGGPPW PAPTGEEEGP RRVEGRRADG SVFPAELSLR ALRRENGGGL VVLFLHDLSA EGGAKSLAES GRAESAFLDV LASELVVPVE AMALALRSSH PDLERVEQAL SLLGQIATDV RGFANLEAGR VALEFAPVEV RAVCTRARAA VLAPAAEFGL KVGVSVAPDT PETILGDEAL LETVLTNLLD CALQFNALDP AAHAALPGSI TLSVRPLDNP PGRLRIEVGC PASEGGRDGL DPASRRRGPI LPGARLRLEP VGSRGRTGTI LVITRRLAEL MGGRVGMESF PGRGTVLWFE LDD //