ID Q2RPG2_RHORT Unreviewed; 456 AA. AC Q2RPG2; DT 24-JAN-2006, integrated into UniProtKB/TrEMBL. DT 24-JAN-2006, sequence version 1. DT 22-FEB-2023, entry version 113. DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438}; DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438}; GN ORFNames=Rru_A3188 {ECO:0000313|EMBL:ABC23983.1}; OS Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / OS NCIMB 8255 / S1). OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales; OC Rhodospirillaceae; Rhodospirillum. OX NCBI_TaxID=269796 {ECO:0000313|EMBL:ABC23983.1, ECO:0000313|Proteomes:UP000001929}; RN [1] {ECO:0000313|EMBL:ABC23983.1, ECO:0000313|Proteomes:UP000001929} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1 RC {ECO:0000313|Proteomes:UP000001929}; RX PubMed=21886856; DOI=10.4056/sigs.1804360; RA Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K., RA Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., RA Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C., RA Mavromatis K., Richardson P., Rohde M., Goker M., Klenk H.P., Zhang Y., RA Roberts G.P., Reslewic S., Schwartz D.C.; RT "Complete genome sequence of Rhodospirillum rubrum type strain (S1)."; RL Stand. Genomic Sci. 4:293-302(2011). CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000230; ABC23983.1; -; Genomic_DNA. DR RefSeq; YP_428270.1; NC_007643.1. DR AlphaFoldDB; Q2RPG2; -. DR STRING; 269796.Rru_A3188; -. DR EnsemblBacteria; ABC23983; ABC23983; Rru_A3188. DR KEGG; rru:Rru_A3188; -. DR PATRIC; fig|269796.9.peg.3301; -. DR eggNOG; COG0642; Bacteria. DR HOGENOM; CLU_000445_42_3_5; -. DR OMA; QVMQRIY; -. DR PhylomeDB; Q2RPG2; -. DR Proteomes; UP000001929; Chromosome. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro. DR CDD; cd06225; HAMP; 1. DR Gene3D; 1.10.287.130; -; 1. DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1. DR InterPro; IPR003660; HAMP_dom. DR InterPro; IPR003594; HATPase_C. DR InterPro; IPR036890; HATPase_C_sf. DR InterPro; IPR005467; His_kinase_dom. DR InterPro; IPR036097; HisK_dim/P_sf. DR InterPro; IPR004358; Sig_transdc_His_kin-like_C. DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1. DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1. DR Pfam; PF02518; HATPase_c; 1. DR PRINTS; PR00344; BCTRLSENSOR. DR SMART; SM00387; HATPase_c; 1. DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1. DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1. DR PROSITE; PS50885; HAMP; 1. DR PROSITE; PS50109; HIS_KIN; 1. PE 4: Predicted; KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABC23983.1}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Reference proteome {ECO:0000313|Proteomes:UP000001929}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABC23983.1}. FT DOMAIN 179..230 FT /note="HAMP" FT /evidence="ECO:0000259|PROSITE:PS50885" FT DOMAIN 238..438 FT /note="Histidine kinase" FT /evidence="ECO:0000259|PROSITE:PS50109" FT REGION 432..456 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 442..456 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 456 AA; 48633 MW; 4EAFCA4982071C8A CRC64; MWLAGALAAT YLVISYAVAE TLERGFDETL AALVDTLTAA AEITDDGTLV LLRDPGDPRF TRAYSGWYWQ MTWGDQVVRS RSLWDQTLVR GEHASDAIHI HRERDPRGRP LEVVERDIFP PRPAAGTPPP SLPAQPVHVM VAGDRTGIEG EIARLQGLLA LCLAGLGGGL LAATFAQVSY GLRPLDRLRA ALHRARDDPS LRLEETQPGE LAPLAQALNA LLDHNASLID RARAHVGNLA HGLKTPLAVL RSAADDGPTV EADMVRAQTA TMGRLVERHL ARARASVGQT AIFSARAPIL AAARRVGATM ALIHCRPLDI TIDGAEDAAF PGAGDDLLEI LGNLMDNACK WAKARVAVHA GREAGRIILT VEDDGPGLAE DEARTAPRRG ARLDDSLPGH GLGLDIVADL AALHGATLTL DRSRLGGLRA TLRLPPAGWG DKPADPRDKG RSRPAE //