ID NTPA_RHORT Reviewed; 201 AA. AC Q2RN61; DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot. DT 24-JAN-2006, sequence version 1. DT 31-MAY-2011, entry version 33. DE RecName: Full=Nucleoside-triphosphatase; DE EC=3.6.1.15; DE AltName: Full=Nucleoside triphosphate phosphohydrolase; DE Short=NTPase; GN OrderedLocusNames=Rru_A3640; OS Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255). OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales; OC Rhodospirillaceae; Rhodospirillum. OX NCBI_TaxID=269796; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 11170 / NCIB 8255; RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., RA Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., RA Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., RA Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., RA Reslewic S., Zhou S., Schwartz D.C.; RT "Complete sequence of the chromosome of Rhodospirillum rubrum ATCC RT 11170."; RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and CC dITP/ITP. Might exclude non-standard purines from DNA precursor CC pool, preventing thus incorporation into DNA and avoiding CC chromosomal lesions (By similarity). CC -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate. CC -!- COFACTOR: Divalent cations (By similarity). CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SIMILARITY: Belongs to the HAM1 NTPase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000230; ABC24434.1; -; Genomic_DNA. DR RefSeq; YP_428721.1; NC_007643.1. DR ProteinModelPortal; Q2RN61; -. DR SMR; Q2RN61; 10-198. DR STRING; Q2RN61; -. DR GeneID; 3837096; -. DR GenomeReviews; CP000230_GR; Rru_A3640. DR KEGG; rru:Rru_A3640; -. DR NMPDR; fig|1085.1.peg.1276; -. DR eggNOG; COG0127; -. DR HOGENOM; HBG697237; -. DR OMA; VYTADWA; -. DR PhylomeDB; Q2RN61; -. DR ProtClustDB; PRK00120; -. DR BioCyc; RRUB269796:RRU_A3640-MONOMER; -. DR GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:EC. DR HAMAP; MF_01405; Nucleoside_triphosp; 1; -. DR InterPro; IPR002637; Ham1p-like. DR InterPro; IPR020922; Nucleoside-triphosphatase. DR PANTHER; PTHR11067; Ham1p_like; 1. DR Pfam; PF01725; Ham1p_like; 1. DR TIGRFAMs; TIGR00042; TIGR00042; 1. PE 3: Inferred from homology; KW Complete proteome; Hydrolase. FT CHAIN 1 201 Nucleoside-triphosphatase. FT /FTId=PRO_1000087380. SQ SEQUENCE 201 AA; 20884 MW; C339D1A4D7F47802 CRC64; MAMSRRLVES PLVVASHNAG KVREIAELIA PFGLEARSAA SLDLPEPEET GSSFVENALL KAHAAARATG LPALADDSGL AVSALGGDPG IYSARWAGPT KDFALAMATI NHLLGDNPDR SAHFVCALAL AWPDGHAETF EGRVDGVLVW PPRGDQGFGY DPMFLGEGAA ETFGEMDPAA KHAISHRARA FALLVAACLG G //