ID RL1_MOOTA Reviewed; 231 AA. AC Q2RFN6; DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot. DT 24-JAN-2006, sequence version 1. DT 23-FEB-2022, entry version 88. DE RecName: Full=50S ribosomal protein L1 {ECO:0000255|HAMAP-Rule:MF_01318}; GN Name=rplA {ECO:0000255|HAMAP-Rule:MF_01318}; OrderedLocusNames=Moth_2471; OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320). OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales; OC Thermoanaerobacteraceae; Moorella group; Moorella. OX NCBI_TaxID=264732; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 39073 / JCM 9320; RX PubMed=18631365; DOI=10.1111/j.1462-2920.2008.01679.x; RA Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C., RA Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.; RT "The complete genome sequence of Moorella thermoacetica (f. Clostridium RT thermoaceticum)."; RL Environ. Microbiol. 10:2550-2573(2008). CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile in CC the ribosome, and is involved in E site tRNA release. CC {ECO:0000255|HAMAP-Rule:MF_01318}. CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it CC controls the translation of the L11 operon by binding to its mRNA. CC {ECO:0000255|HAMAP-Rule:MF_01318}. CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP- CC Rule:MF_01318}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family. CC {ECO:0000255|HAMAP-Rule:MF_01318}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000232; ABC20753.1; -; Genomic_DNA. DR RefSeq; WP_011393948.1; NC_007644.1. DR RefSeq; YP_431296.1; NC_007644.1. DR SMR; Q2RFN6; -. DR STRING; 264732.Moth_2471; -. DR EnsemblBacteria; ABC20753; ABC20753; Moth_2471. DR GeneID; 61291196; -. DR KEGG; mta:Moth_2471; -. DR PATRIC; fig|264732.11.peg.2689; -. DR eggNOG; COG0081; Bacteria. DR HOGENOM; CLU_062853_0_0_9; -. DR OMA; GWTDVDV; -. DR Proteomes; UP000007053; Chromosome. DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule. DR CDD; cd00403; Ribosomal_L1; 1. DR Gene3D; 3.40.50.790; -; 1. DR HAMAP; MF_01318_B; Ribosomal_L1_B; 1. DR InterPro; IPR005878; Ribosom_L1_bac-type. DR InterPro; IPR002143; Ribosomal_L1. DR InterPro; IPR023674; Ribosomal_L1-like. DR InterPro; IPR028364; Ribosomal_L1/biogenesis. DR InterPro; IPR016095; Ribosomal_L1_3-a/b-sand. DR InterPro; IPR023673; Ribosomal_L1_CS. DR Pfam; PF00687; Ribosomal_L1; 1. DR PIRSF; PIRSF002155; Ribosomal_L1; 1. DR SUPFAM; SSF56808; SSF56808; 1. DR TIGRFAMs; TIGR01169; rplA_bact; 1. DR PROSITE; PS01199; RIBOSOMAL_L1; 1. PE 3: Inferred from homology; KW Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein; KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding. FT CHAIN 1..231 FT /note="50S ribosomal protein L1" FT /id="PRO_0000308048" SQ SEQUENCE 231 AA; 25012 MW; 84A0D0B590FE5691 CRC64; MPKHGKRYRE VSKLVSRQEL YEPDEAIELL KKTASAKFDE TVEVAVKLGV DPRHADQQVR GTVVLPNGTG KTRRVLVFAK GDKAKEAEEA GADFVGAEDL VEKIQGGWLD FDVAIATPDM MGLVGRLGRI LGPRGLMPNP KAGTVTMDIA RAVKEVKAGK IEFRVDKTAI IHAPIGKASF EASKLKENFQ ALMDALLRAK PATAKGQYLK SVSLATTMGP GIRVNPLRAV K //