ID RL1_MOOTA Reviewed; 231 AA. AC Q2RFN6; DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot. DT 24-JAN-2006, sequence version 1. DT 28-JUN-2011, entry version 42. DE RecName: Full=50S ribosomal protein L1; GN Name=rplA; OrderedLocusNames=Moth_2471; OS Moorella thermoacetica (strain ATCC 39073). OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales; OC Thermoanaerobacteraceae; Moorella group; Moorella. OX NCBI_TaxID=264732; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 39073; RX PubMed=18631365; DOI=10.1111/j.1462-2920.2008.01679.x; RA Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C., RA Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.; RT "The complete genome sequence of Moorella thermoacetica (f. RT Clostridium thermoaceticum)."; RL Environ. Microbiol. 10:2550-2573(2008). CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile CC in the ribosome, and is involved in E site tRNA release (By CC similarity). CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it CC controls the translation of the L11 operon by binding to its mRNA CC (By similarity). CC -!- SUBUNIT: Part of the 50S ribosomal subunit. CC -!- SIMILARITY: Belongs to the ribosomal protein L1P family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000232; ABC20753.1; -; Genomic_DNA. DR RefSeq; YP_431296.1; NC_007644.1. DR HSSP; Q5SLP7; 1YL3. DR ProteinModelPortal; Q2RFN6; -. DR SMR; Q2RFN6; 2-226. DR STRING; Q2RFN6; -. DR GeneID; 3831205; -. DR GenomeReviews; CP000232_GR; Moth_2471. DR KEGG; mta:Moth_2471; -. DR NMPDR; fig|264732.9.peg.2503; -. DR eggNOG; COG0081; -. DR HOGENOM; HBG297400; -. DR OMA; DFDRCIA; -. DR PhylomeDB; Q2RFN6; -. DR ProtClustDB; PRK05424; -. DR BioCyc; MTHE264732:MOTH_2471-MONOMER; -. DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. DR GO; GO:0006412; P:translation; IEA:InterPro. DR HAMAP; MF_01318_B; Ribosomal_L1_B; 1; -. DR InterPro; IPR005878; Ribosom_L1_bac-type. DR InterPro; IPR002143; Ribosomal_L1. DR InterPro; IPR016094; Ribosomal_L1_2-a/b-sand. DR InterPro; IPR016095; Ribosomal_L1_3-a/b-sand. DR InterPro; IPR023673; Ribosomal_L1_CS. DR InterPro; IPR023674; Ribosomal_L1_SF. DR Gene3D; G3DSA:3.30.190.20; Ribosomal_L1_2-a/b-sand; 2. DR Gene3D; G3DSA:3.40.50.790; Ribosomal_L1_3-a/b-sand; 1. DR Pfam; PF00687; Ribosomal_L1; 1. DR PIRSF; PIRSF002155; Ribosomal_L1; 1. DR SUPFAM; SSF56808; Ribosomal_L1; 1. DR TIGRFAMs; TIGR01169; RplA_bact; 1. DR PROSITE; PS01199; RIBOSOMAL_L1; 1. PE 3: Inferred from homology; KW Complete proteome; Repressor; Ribonucleoprotein; Ribosomal protein; KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding. FT CHAIN 1 231 50S ribosomal protein L1. FT /FTId=PRO_0000308048. SQ SEQUENCE 231 AA; 25012 MW; 84A0D0B590FE5691 CRC64; MPKHGKRYRE VSKLVSRQEL YEPDEAIELL KKTASAKFDE TVEVAVKLGV DPRHADQQVR GTVVLPNGTG KTRRVLVFAK GDKAKEAEEA GADFVGAEDL VEKIQGGWLD FDVAIATPDM MGLVGRLGRI LGPRGLMPNP KAGTVTMDIA RAVKEVKAGK IEFRVDKTAI IHAPIGKASF EASKLKENFQ ALMDALLRAK PATAKGQYLK SVSLATTMGP GIRVNPLRAV K //