ID Q2Q0K7_DROME Unreviewed; 311 AA. AC Q2Q0K7; DT 24-JAN-2006, integrated into UniProtKB/TrEMBL. DT 24-JAN-2006, sequence version 1. DT 20-JAN-2009, entry version 19. DE SubName: Full=R2D2; GN Name=r2d2; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=G196; RX PubMed=16546082; DOI=10.1016/j.cub.2006.01.065; RA Obbard D.J., Jiggins F.M., Halligan D.L., Little T.J.; RT "Natural selection drives extremely rapid evolution in antiviral RNAi RT genes."; RL Curr. Biol. 16:580-585(2006). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ252345; ABB77177.1; -; Genomic_DNA. DR PRIDE; Q2Q0K7; -. DR FlyBase; FBgn0031951; r2d2. DR HOGENOM; Q2Q0K7; -. DR ArrayExpress; Q2Q0K7; -. DR GO; GO:0051607; P:defense response to virus; IMP:FlyBase. DR GO; GO:0035087; P:RNA interference, siRNA loading onto RISC; IDA:FlyBase. DR GO; GO:0035087; P:RNA interference, siRNA loading onto RISC; TAS:FlyBase. DR InterPro; IPR001159; Ds-RNA_bd. DR InterPro; IPR014720; dsRNA-bd-like. DR Gene3D; G3DSA:3.30.160.20; dsRNA-bd-like; 2. DR Pfam; PF00035; dsrm; 2. DR SMART; SM00358; DSRM; 2. DR PROSITE; PS50137; DS_RBD; 2. PE 2: Evidence at transcript level; KW Complete proteome. SQ SEQUENCE 311 AA; 35043 MW; 65FF56CE07A830A1 CRC64; MDNKSAVSAL QEFCARTQIN LPTYSFIPGE DGGYVCKVEL LEIEALGNGR SKRDAKHLAA SNILRKIQLL PGIHGLMKDS TVGDLDEELT NLNRDMVKEL RDYCVRREMP LPCIEVVQQS GTPSAPEFVA CCSVASIVRY GKSDKKKDAR QRAAIEMLAL ISSNSDNLRP DQMQVASTSK LKVVDMEESM EELEASRRKK FTTYWELKEA GSVDHTGMRL CDRHNYFKNF YPTLKKEAIE AINSDEYESS KDKAMDVMSS LKITPKISEV ESSSLVPLLS VELNCAFDVV LMAKETDIYD HIIDYFRTML I //