ID Q2M4V7_9HYME Unreviewed; 138 AA. AC Q2M4V7; DT 21-FEB-2006, integrated into UniProtKB/TrEMBL. DT 21-FEB-2006, sequence version 1. DT 19-MAR-2014, entry version 40. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Platyscapa sp. ZFJ-2005b. OG Mitochondrion. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; OC Chalcidoidea; Agaonidae; Agaoninae; Platyscapa. OX NCBI_TaxID=318092; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=16364663; DOI=10.1016/j.ympev.2005.11.008; RA Jiang Z.F., Huang D.W., Zhu C.D., Zhen W.Q.; RT "New insights into the phylogeny of fig pollinators using Bayesian RT analyses."; RL Mol. Phylogenet. Evol. 38:306-315(2006). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY842427; AAX47331.1; -; Genomic_DNA. DR ProteinModelPortal; Q2M4V7; -. DR UniPathway; UPA00705; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:1902600; P:hydrogen ion transmembrane transport; IEA:GOC. DR GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway. DR Gene3D; 1.20.210.10; -; 1. DR InterPro; IPR000883; Cyt_c_Oxase_su1. DR InterPro; IPR023616; Cyt_c_Oxase_su1_dom. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; SSF81442; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 138 138 SQ SEQUENCE 138 AA; 15130 MW; 416D69A29F057848 CRC64; FGLISHMICN ESMKKEVFGA LAMIYAMSAI GLLGFIVWGH HMFTVGMDID TRAYFTSATM IIAVPTGIKI FSWLASMSGI KIKSNVSHLW ILGFVFLFTL GGLTGVILAN SSIDIVLHDT YYVVAHFHYV LSMGAVFA //