ID Q2M3M2_HUMAN Unreviewed; 681 AA. AC Q2M3M2; DT 21-FEB-2006, integrated into UniProtKB/TrEMBL. DT 21-FEB-2006, sequence version 1. DT 10-JUL-2007, entry version 11. DE SLC5A9 protein. GN Name=SLC5A9; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Lung; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Lung; RG NIH MGC Project; RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein (By CC similarity). CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC CC 2.A.21) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC104857; AAI04858.1; -; mRNA. DR EMBL; BC104863; AAI04864.1; -; mRNA. DR UniGene; Hs.37890; -. DR HGNC; HGNC:22146; SLC5A9. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005215; F:transporter activity; IEA:InterPro. DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. DR InterPro; IPR001734; Na/solut_symport. DR PANTHER; PTHR11819; Na/solut_symport; 2. DR Pfam; PF00474; SSF; 1. DR TIGRFAMs; TIGR00813; sss; 1. DR PROSITE; PS00456; NA_SOLUT_SYMP_1; UNKNOWN_1. DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1. KW Ion transport; Sodium transport; Transmembrane; Transport. SQ SEQUENCE 681 AA; 74091 MW; EAAE22F3E0597DEF CRC64; MSKELAAMGP GASGDGVRTE TAPHIALDSR VGLHAYDISV VVIYFVFVIA VGIWSSIRAS RGTIGGYFLA GRSMSWWPIG ASLMSSNVGS GLFIGLAGTG AAGGLAVGGF EWNATWLLLA LGWVFVPVYI AAGVVTMPQY LKKRFGGQRI QVYMSVLSLI LYIFTKISTD IFSGALFIQM ALGWNLYLST GILLVVTAVY TIAGGLMAVI YTDALQTVIM VGGALVLMFL GFQDVGWYPG LEQRYRQAIP NVTVPNTTCH LPRPDAFHML RDPVSGDIPW PGLIFGLTVL ATWCWCTDQV IVQRSLSAKS LSHAKGGSVL GGYLKILPMF FIVMPGMISR ALFPDEVGCV DPDVCQRICG ARVGCSNIAY PKLVMALMPV GLRGLMIAVI MAALMSSLTS IFNSSSTLFT IDVWQRFRRK STEQELMVVG RVFVVFLVVI SILWIPIIQS SNSGQLFDYI QAVTSYLAPP ITALFLLAIF CKRVTEPGAF WGLVFGLGVG LLRMILEFSY PAPACGEVDR RPAVLKDFHY LYFAILLCGL TAIVIVIVSL CTTPIPEEQL TRLTWWTRNC PLSELEKEAH ESTPEISERP AGECPAGGGA AENSSLGQEQ PEAPSRSWGK LLWSWFCGLS GTPEQALSPA EKAALEQKLT SIEEEPLWRH VCNINAVLLL AINIFLWGYF A //