ID PIPNA_BOVIN Reviewed; 270 AA. AC Q2HJ54; Q9TR37; DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 3. DT 10-FEB-2009, entry version 22. DE RecName: Full=Phosphatidylinositol transfer protein alpha isoform; DE Short=PtdIns transfer protein alpha; DE Short=PtdInsTP; DE Short=PI-TP-alpha; DE AltName: Full=Phosphatidylinositol-transfer protein 35 kDa isoform; DE Short=PI-TP 35 kda isoform; GN Name=PITPNA; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Hereford; TISSUE=Uterus; RG NIH - Mammalian Gene Collection (MGC) project; RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. RN [2] RP PROTEIN SEQUENCE OF 2-22. RC TISSUE=Brain; RX MEDLINE=95382786; PubMed=7654206; RA de Vries K.J., Heinrichs A.A., Cunningham E., Brunink F., RA Westerman J., Somerharju P.J., Cockcroft S., Wirtz K.W., Snoek G.T.; RT "An isoform of the phosphatidylinositol-transfer protein transfers RT sphingomyelin and is associated with the Golgi system."; RL Biochem. J. 310:643-649(1995). CC -!- FUNCTION: Catalyzes the transfer of PtdIns and phosphatidylcholine CC between membranes (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the PtdIns transfer protein family. Class I CC subfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC113306; AAI13307.1; -; mRNA. DR IPI; IPI00695148; -. DR PIR; A48214; A48214. DR PIR; S58431; S58431. DR RefSeq; NP_001040047.1; -. DR UniGene; Bt.22547; -. DR SMR; Q2HJ54; 1-269. DR Ensembl; ENSBTAG00000011480; Bos taurus. DR GeneID; 616550; -. DR KEGG; bta:616550; -. DR HOVERGEN; Q2HJ54; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:InterPro. DR InterPro; IPR001666; PI_transfer. DR PANTHER; PTHR10658; PI_transfer; 1. DR Pfam; PF02121; IP_trans; 1. DR PRINTS; PR00391; PITRANSFER. PE 1: Evidence at protein level; KW Cytoplasm; Direct protein sequencing; Lipid-binding; Phosphoprotein; KW Transport. FT INIT_MET 1 1 Removed. FT CHAIN 2 270 Phosphatidylinositol transfer protein FT alpha isoform. FT /FTId=PRO_0000269200. FT MOD_RES 57 57 Phosphotyrosine (By similarity). SQ SEQUENCE 270 AA; 31849 MW; FFE53A8F4D9F87CD CRC64; MVLLKEYRVI LPVSVEEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DGEKGQYTHK IYHLQSKVPT FVRMLAPEGA LNIHEKAWNA YPYCRTVITN EYMKEDFLIK IETWHKPDLG TLENVHKLEP EAWKHVEVIY IDIADRSQVL SKDYKAEEDP AKYKSIKTGR GPLGPNWKQE LVNQKDCPYM CAYKLVTVKF KWWGLQNKVE NFIHKQERRL FTNFHRQLFC WLDKWVDLTM DDIRRMEDET KRQLDEMRQK DPVKGMTADD //