ID PYRH_NOVAD Reviewed; 244 AA. AC Q2G8K8; DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot. DT 21-MAR-2006, sequence version 1. DT 15-JAN-2008, entry version 20. DE Uridylate kinase (EC 2.7.4.-) (UK) (Uridine monophosphate kinase) (UMP DE kinase). GN Name=pyrH; OrderedLocusNames=Saro_1371; OS Novosphingobium aromaticivorans (strain DSM 12444). OC Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; OC Sphingomonadaceae; Novosphingobium. OX NCBI_TaxID=279238; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., RA Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., RA Fredrickson J., Balkwill D., Romine M.F., Richardson P.; RT "Complete sequence of Novosphingobium aromaticivorans DSM 12444."; RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the phosphorylation of UMP to UDP (By CC similarity). CC -!- CATALYTIC ACTIVITY: ATP + UMP = ADP + UDP. CC -!- PATHWAY: Nucleotide biosynthesis; CTP biosynthesis; UDP from UMP CC (UMPK route): step 1/1. CC -!- SIMILARITY: Belongs to the UMP kinase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000248; ABD25815.1; -; Genomic_DNA. DR RefSeq; YP_496649.1; -. DR GeneID; 3917825; -. DR GenomeReviews; CP000248_GR; Saro_1371. DR KEGG; nar:Saro_1371; -. DR HAMAP; MF_01220; -; 1. DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase. DR InterPro; IPR011817; PyrH_bact. DR Gene3D; G3DSA:3.40.1160.10; Aa_kinase; 1. DR Pfam; PF00696; AA_kinase; 1. DR PIRSF; PIRSF005650; Uridylate_kin; 1. DR TIGRFAMs; TIGR02075; pyrH_bact; 1. PE 3: Inferred from homology; KW Complete proteome; Kinase; Pyrimidine biosynthesis; Transferase. FT CHAIN 1 244 Uridylate kinase. FT /FTId=PRO_1000053968. SQ SEQUENCE 244 AA; 26248 MW; FAF42119402C389F CRC64; MSLPSCVPGY RRILLKLSGE VLMGEQQFGI DTDYVARVAQ EVKDARDSGL EICLVIGGGN IFRGMAGAAK GMDRAQADYM GMLATVMNAL AMQSALEQLG VPTRVQSAIE MDKVCEPVIR RRAERHLEKG RIVIFAAGVG APYFTTDSGA ALRAAEMKCD ALLKGTSVDG VYNADPKKDP AAKRYETVDY DTVLADNLKV MDASAVALCR DNNIPIVVFS IRERGNLARV LAGEGTQTTV KKEA //