ID   AL9A1_PIG               Reviewed;          69 AA.
AC   Q29228;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   12-JUN-2007, entry version 36.
DE   4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) (TMABADH)
DE   (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) (Fragment).
GN   Name=ALDH9A1; Synonyms=ALDH9;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Small intestine;
RX   MEDLINE=96327607; PubMed=8672129; DOI=10.1007/s003359900153;
RA   Winteroe A.K., Fredholm M., Davies W.;
RT   "Evaluation and characterization of a porcine small intestine cDNA
RT   library: analysis of 839 clones.";
RL   Mamm. Genome 7:509-517(1996).
CC   -!- FUNCTION: Converts gamma-trimethylaminobutyraldehyde into gamma-
CC       butyrobetaine (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4-trimethylammoniobutanal + NAD(+) + H(2)O =
CC       4-trimethylammoniobutanoate + NADH.
CC   -!- CATALYTIC ACTIVITY: An aldehyde + NAD(+) + H(2)O = an acid + NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; carnitine biosynthesis.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; F14819; CAA23277.1; -; mRNA.
DR   HSSP; P56533; 1A4S.
DR   GO; GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogena...; IEA:EC.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
DR   InterPro; IPR002086; Ald_DH.
DR   InterPro; IPR015590; Aldehyde_dehyd.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; PARTIAL.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; PARTIAL.
KW   NAD; Oxidoreductase.
FT   CHAIN        <1    >69       4-trimethylaminobutyraldehyde
FT                                dehydrogenase.
FT                                /FTId=PRO_0000056487.
FT   NON_TER       1      1
FT   NON_TER      69     69
SQ   SEQUENCE   69 AA;  7674 MW;  D30F604E1BD039D1 CRC64;
     EPATGRVIAT LTCSGEKEVN LAVQDAKAAF KIWSQKSGME RCRILLEAAR XIRERKEEIA
     TMETINNGK
//