ID HM21_CAEEL STANDARD; PRT; 495 AA. AC Q22811; Q8WQE1; DT 16-OCT-2001 (Rel. 40, Created) DT 15-JUN-2002 (Rel. 41, Last sequence update) DT 15-JUN-2002 (Rel. 41, Last annotation update) DE Homeobox protein ceh-21. GN CEH-21 OR T26C11.6. OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Bristol N2; RA Burglin T.R., Cassata G.; RT "Loss and gain of domains during evolution of cut superclass homeobox RT genes."; RL Int. J. Dev. Biol. 46:0-0(2002). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=Bristol N2; RA Martin J.; RL Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases. RN [3] RP REVISIONS. RA Waterston R.; RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases. RN [4] RP SEQUENCE OF 313-495 FROM N.A. RC STRAIN=Bristol N2; RX MEDLINE=98256275; PubMed=9593691; RA Lannoy V.J., Buerglin T.R., Rousseau G.G., Lemaigre F.P.; RT "Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding RT properties, contain a bifunctional homeodomain, and define the new RT ONECUT class of homeodomain proteins."; RL J. Biol. Chem. 273:13552-13562(1998). CC -!- SUBCELLULAR LOCATION: Nuclear (Potential). CC -!- SIMILARITY: CONTAINS 1 CUT DOMAIN. CC -!- SIMILARITY: BELONGS TO THE CUT HOMEOBOX FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ427855; CAD20808.1; -. DR EMBL; U41017; AAC48216.2; -. DR EMBL; AF023470; AAB86814.1; -. DR TRANSFAC; T03297; -. DR WormPep; T26C11.6; CE29823. DR InterPro; IPR003350; Hmoeo_CUT. DR InterPro; IPR001356; Homeobox. DR Pfam; PF00046; homeobox; 1. DR Pfam; PF02376; CUT; 1. DR ProDom; PD000010; Homeobox; 1. DR SMART; SM00389; HOX; 1. DR PROSITE; PS00027; HOMEOBOX_1; FALSE_NEG. DR PROSITE; PS50071; HOMEOBOX_2; 1. KW Homeobox; DNA-binding; Nuclear protein. FT DNA_BIND 284 370 CUT. FT DNA_BIND 389 449 HOMEOBOX. SQ SEQUENCE 495 AA; 54823 MW; C4FFA0984D0DAA08 CRC64; MSQQFQASSG TGSASLREFK TEHEDLREDL PYSTLRTLFG ITLDKDASQA LNIALLLYGH NYPQQVVPPE RNYAELDAQL ESVVLEDHTA ESTMEPGVSA TVTEQLEEKS DKSSDGDGTS KRLTRSLKSV ENETEEDHEE KEDEAPQSSR RESTRLKRKL LESQKTVQTT GNSSRASSKS QEKEVPGTKS QCAPKIRTTP EQSKAATKRQ SSTTVRASST CGSSVSSTST VSSPDYTAKK GRATETPKLE ELAPKKQSSA TPKPGGEVCV WDGVQIGDLS AQMNAQIGDD EELDTVDIAR RILSELKERC IPQTALAEKI LARSQGTLSD LLRMPKPWSV MKNGRATFQR MSNWLGLDPD VRRALCFLPK EDVARITGLD EPTPAKRKKT VKVIRLTFTE TQLKSLQKSF QQNHRPTREM RQKLSATLEL DFSTVGNFFM NSRRRLRIDQ QISRSSRSTG NGADTEDELD EEDVVVENVI ADATDASNQP GPSHL //