ID SET1_CAEEL Reviewed; 242 AA. AC Q22795; DT 23-APR-2003, integrated into UniProtKB/Swiss-Prot. DT 01-JAN-1999, sequence version 2. DT 24-JUL-2007, entry version 41. DE Protein set-1. GN Name=set-1; ORFNames=T26A5.7; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [2] RP SEQUENCE REVISION. RG WormBase consortium; RL Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. RN [3] RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE. RX MEDLINE=22114964; PubMed=12119097; DOI=10.1016/S0378-1119(02)00671-6; RA Terranova R., Pujol N., Fasano L., Djabali M.; RT "Characterisation of set-1, a conserved PR/SET domain gene in RT Caenorhabditis elegans."; RL Gene 292:33-41(2002). CC -!- FUNCTION: Essential protein probably involved in chromatin CC modification and/or regulation. CC -!- SUBCELLULAR LOCATION: Nucleus. CC -!- TISSUE SPECIFICITY: In embryos, it is expressed ubiquitously. In CC late embryos, it is expressed in hypodermal seam cells. In L3 and CC L4 larvae and thereafter, it is expressed in vulval precursor CC cells. In adult males, it is also expressed in 6 unidentified CC posterior cells. CC -!- DEVELOPMENTAL STAGE: Highly expressed in eggs, then decreases. CC -!- SIMILARITY: Contains 1 SET domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U00043; AAC77512.1; -; Genomic_DNA. DR PIR; T34384; T34384. DR UniGene; Cel.7462; -. DR Ensembl; T26A5.7; Caenorhabditis elegans. DR KEGG; cel:T26A5.7a; -. DR WormBase; WBGene00004781; set-1. DR WormPep; T26A5.7; CE19602. DR InterPro; IPR001214; SET. DR Pfam; PF00856; SET; 1. DR SMART; SM00317; SET; 1. DR PROSITE; PS50280; SET; 1. PE 2: Evidence at transcript level; KW Complete proteome; Developmental protein; Nucleus. FT CHAIN 1 242 Protein set-1. FT /FTId=PRO_0000097694. FT DOMAIN 103 230 SET. FT COMPBIAS 18 21 Poly-Ala. FT COMPBIAS 38 43 Poly-Ser. SQ SEQUENCE 242 AA; 27568 MW; 0F752B79505AFA99 CRC64; MKVAAKKLAT SRMRKDRAAA ASPSSDIENS ENPSSLASHS SSSGRMTPSK NTRSRKGVSV KDVSNHKITE FFQVRRSNRK TSKQISDEAK HALRDTVLKG TNERLLEVYK DVVKGRGIRT KVNFEKGDFV VEYRGVMMEY SEAKVIEEQY SNDEEIGSYM YFFEHNNKKW CIDATKESPW KGRLINHSVL RPNLKTKVVE IDGSHHLILV ARRQIAQGEE LLYDYGDRSA ETIAKNPWLV NT //