ID Q1T7A3_HUMAN Unreviewed; 417 AA. AC Q1T7A3; DT 16-MAY-2006, integrated into UniProtKB/TrEMBL. DT 16-MAY-2006, sequence version 1. DT 07-NOV-2018, entry version 27. DE SubName: Full=CD177 {ECO:0000313|EMBL:BAE93254.1}; DE SubName: Full=CD177 antigen {ECO:0000313|EMBL:AXQ06579.1}; GN Name=CD177 {ECO:0000313|EMBL:BAE93254.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAE93254.1}; RN [1] {ECO:0000313|EMBL:BAE93254.1} RP NUCLEOTIDE SEQUENCE. RA Odagiri M., Watanabe Y., Kamata H.N., Mazda T., Okazaki H., RA Ohshima H., Juji T.; RT "Loss of HNA-2a(NB1,CD177) expression on the neutrophil surface caused RT by a nonsense mutation in the carboxyl-terminal signal for GPI RT modification."; RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AXQ06579.1} RP NUCLEOTIDE SEQUENCE. RA Chu C.-C.; RT "A nonsense mutation at CD177 c.1254G>A is associate with HNA-2 null RT phenotype in Asian populations."; RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MG021197; AXQ06579.1; -; Genomic_DNA. DR EMBL; AB237911; BAE93254.1; -; mRNA. DR UniGene; Hs.232165; -. DR PeptideAtlas; Q1T7A3; -. DR eggNOG; ENOG410J207; Eukaryota. DR eggNOG; ENOG4111D7X; LUCA. DR HOVERGEN; HBG081064; -. DR InterPro; IPR016054; LY6_UPA_recep-like. DR Pfam; PF00021; UPAR_LY6; 2. PE 2: Evidence at transcript level; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 417 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5004196813. FT DOMAIN 133 208 UPAR/Ly6. {ECO:0000259|Pfam:PF00021}. FT DOMAIN 325 394 UPAR/Ly6. {ECO:0000259|Pfam:PF00021}. SQ SEQUENCE 417 AA; 44326 MW; 9AF6585BE48F8433 CRC64; MSAVLLLALL GFILPLPGVQ ALLCQFGTVQ HVWKVSDLPR QWTPKNTSCD SGLGCQDTLM LIESGPQVSL VLSKGCTEAK DQEPRVTEHR MGPGLSLISY TFVCRQEDFC NNLVNSLPLW APQPPADPGS LRCPVCLSME GCLEGTTEEI CPKGTTHCYD GLLRLRGGGI FSNLRVQGCM PQPGCNLLNG TQEIGPVGMT ENCNRKDFLT CHRGTTIMTH GNLAQEPTDW TTSNTEMCEV GQVCQEMLLL IDVGLTSTLV GTKGCSTVGA QNSQKTTIHS APPGVLVASY THFCSSDLCN SASSSSVLLN SLPPQAAPVP GDRQCPTCVQ PLGTCSSGSP RMTCPRGATH CYDGYIHLSG GGLSTKMSIQ GCVAQPSSFL LNHTRQIGIF SAREKRDVQP PASQHEGGGA EGLESLT //